Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13845793 | 0.84 | POLB (0.55) | MEN1KMT2AMMP9MMP2POLB | |
| SCHEMBL7122131 | 0.81 | MEN1 (0.54) | MEN1KMT2AMMP9MMP2POLB | |
| SCHEMBL7069632 | 0.81 | ALDH1A1 (0.65) | MEN1KMT2AMMP9MMP2POLB | |
| SCHEMBL6710573 | 0.80 | GAA (0.60) | MMP9MMP2POLBKDM4EMAPK1 | |
| SCHEMBL5082404 | 0.80 | MEN1 (0.61) | MEN1KMT2AMMP9MMP2POLB | |
| SCHEMBL4015124 | 0.80 | MEN1 (0.61) | MEN1KMT2AMMP9MMP2POLB | |
| SCHEMBL13845789 | 0.79 | MEN1 (0.55) | MEN1KMT2AMMP9MMP2POLB | |
| SCHEMBL4074349 | 0.76 | KMT2A (0.57) | MEN1KMT2AMMP9MMP2POLB | |
| SCHEMBL7069024 | 0.76 | MEN1 (0.54) | MEN1KMT2AMMP9MMP2POLB | |
| SCHEMBL25243550 | 0.72 | MEN1 (0.71) | MEN1KMT2AMMP9MMP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538245-B2 | Process for the manufacture of an enantiopure compound | SOLVAY S.A. (BE) | 2009-05-26 | — | — | US | disclosed |
| US-7538245-B2 | Process for the manufacture of an enantiopure compound | SOLVAY S.A. (BE) | 2009-05-26 | — | — | US | disclosed |
| US-20070027326-A1 | Process for the manufacture of an enantiopure compound | SOLVAY S.A. (BE) | 2007-02-01 | — | — | US | disclosed |
| US-20070027326-A1 | Process for the manufacture of an enantiopure compound | SOLVAY S.A. (BE) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027326-A1 | Process for the manufacture of an enantiopure compound | AMD1, DAO, DDC | MEN1 3808/4885KMT2A 3516/4885MMP9 2504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.