Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162491 | 0.94 | TSHR (0.42) | TSHRSMN1; SMN2TP53HSD11B1PCSK9 | |
| SCHEMBL10419163 | 0.91 | TSHR (0.41) | TSHRSMN1; SMN2TP53HSD11B1PCSK9 | |
| Lithium Ion SCHEMBL9003332 | 0.91 | TSHR (0.41) | TSHRSMN1; SMN2TP53HSD11B1PCSK9 | |
| Tetrylammonium SCHEMBL10784307 | 0.88 | TSHR (0.37) | DNM1TSHRSMN1; SMN2MEN1KMT2A | |
| Tetrabuthylammonium SCHEMBL10782335 | 0.86 | SLC22A1 (0.44) | DNM1TSHRSMN1; SMN2MEN1KMT2A | |
| Tetramethylammonium Ion SCHEMBL8574973 | 0.85 | DNM1 (0.44) | DNM1TSHRSMN1; SMN2MEN1KMT2A | |
| Tetramethylammonium Ion SCHEMBL1276928 | 0.83 | DNM1 (0.39) | DNM1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL309096 | 0.78 | TP53 (0.42) | DNM1TSHRSMN1; SMN2MEN1KMT2A | |
| Tetramethylammonium Ion SCHEMBL6435666 | 0.78 | TP53 (0.36) | DNM1TSHRSMN1; SMN2MEN1KMT2A | |
| Tetramethylammonium Ion SCHEMBL8566540 | 0.78 | DNM1 (0.50) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371466-B2 | Polymerisation initiators, polymerisable compositions, and uses thereof for bonding low surface energy substrates | LOCTITE (R & D) LIMITED (IE) | 2008-05-13 | — | — | US | disclosed |
| WO-2003089536-A3 | POLYMERISATION INITIATORS BASED ON AMMONIUM TETRAALKYL BORANES, POLYMERISABLE COMPOSITIONS, AND USES THEREOF FOR BONDING LOW SURFACE ENERGY SUBSTRATES | LOCTITE R & D LTD (IE) | 2004-03-25 | — | — | WO | disclosed |
| US-20030226472-A1 | Polymerisation initiators, polymerisable compositions, and uses thereof for bonding low surface energy substrates | LOCTITE (R&D) LIMITED | 2003-12-11 | — | — | US | disclosed |
| WO-2003089536-A2 | POLYMERISATION INITIATORS BASED ON AMMONIUM TETRAALKYL BORANES, POLYMERISABLE COMPOSITIONS, AND USES THEREOF FOR BONDING LOW SURFACE ENERGY SUBSTRATES | LOCTITE (R & D) LIMITED (IE) | 2003-10-30 | — | — | WO | disclosed |
| WO-2003089536-A2 | POLYMERISATION INITIATORS BASED ON AMMONIUM TETRAALKYL BORANES, POLYMERISABLE COMPOSITIONS, AND USES THEREOF FOR BONDING LOW SURFACE ENERGY SUBSTRATES | LOCTITE (R & D) LIMITED (IE) | 2003-10-30 | — | — | WO | disclosed |