Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082745 | 1.00 | FAAH (0.39) | FAAHHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL1254167 | 0.99 | FAAH (0.39) | FAAHHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL1254161 | 0.99 | FAAH (0.39) | FAAHHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5082718 | 0.94 | FAAH (0.38) | FAAH | |
| SCHEMBL5082706 | 0.94 | FAAH (0.38) | FAAH | |
| SCHEMBL1254612 | 0.93 | MEN1 (0.39) | FAAH | |
| SCHEMBL1254616 | 0.93 | MEN1 (0.39) | FAAH | |
| Hydrochloric Acid SCHEMBL1253109 | 0.93 | FAAH (0.37) | FAAH | |
| Hydrochloric Acid SCHEMBL1253105 | 0.93 | FAAH (0.37) | FAAH | |
| SCHEMBL727092 | 0.88 | TRPM8 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | claimed |