SCHEMBL5080025

SCHEMBL5080025

CCCCCOCC1(COC)c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.41
CNR2 P34972 1/20 0.40
NPSR1 Q6W5P4 4/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LTA4H P09960 1/20 0.35
PTPN1 P18031 1/20 0.35
TSHR P16473 2/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
APAF1 O14727 1/20 0.32
RAD52 P43351 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20995914 0.89 PDK2 (0.44) PDK2CNR2NPSR1CYP2C9CYP2C19
SCHEMBL30322706 0.89 PDK2 (0.44) PDK2CNR2NPSR1CYP2C9CYP2C19
SCHEMBL5082827 0.82 APEX1 (0.36) PDK2CYP2C9TSHRCYP3A4ALDH1A1
SCHEMBL30322467 0.82 PDK2 (0.40) PDK2CNR2NPSR1CYP2C9CYP2C19
SCHEMBL20995933 0.82 PDK2 (0.40) PDK2CNR2NPSR1CYP2C9CYP2C19
SCHEMBL233774 0.82 APEX1 (0.42) PDK2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL29415598 0.82 APEX1 (0.42) PDK2CYP2C9CYP2C19MEN1KMT2A
SCHEMBL15689425 0.81 MMP2 (0.40) PDK2NPSR1CYP2C9CYP2C19MEN1
SCHEMBL6512868 0.80 APEX1 (0.37) PDK2CYP2C9TSHRCYP3A4MAPK1
Lithium SCHEMBL31124519 0.80 APEX1 (0.41) PDK2CYP2C9CYP2C19MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364305-B2 Polyolefin and a process for preparing the same RELIANCE INDUSTRIES LIMITED (IN) 2019-07-30 US claimed
US-20180312615-A1 A Polyolefin And A Process For Preparing The Same RELIANCE INDUSTRIES LIMITED (IN) 2018-11-01 US claimed
US-20170121430-A1 Ziegler-Natta Catalyst Composition And A Process For Its Preparation RELIANCE INDUSTRIES LIMITED (IN) 2017-05-04 US claimed
WO-2015177732-A1 A ZIEGLER-NATTA CATALYST COMPOSITION AND A PROCESS FOR ITS PREPARATION RELIANCE INDUSTRIES LIMITED (IN) 2015-11-26 WO claimed
EP-1260523-B1 CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS CHINA PETROCHEMICAL CORP (CN) 2013-01-23 EP claimed
US-7049377-B1 1,3-diethers and components and catalysts for the polymerization of olefins, containing said diethers BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2006-05-23 US claimed
US-7022640-B2 1,3-diethers and components and catalysts for the polymerization of olefins, containing said diethers BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2006-04-04 US claimed
US-20040235645-A1 1,3-Diethers and components and catalysts for the polymerization of olefins, containing said diethers MORINI GIAMPIERO (IT) 2004-11-25 US claimed
US-6683017-B2 SOLID CATALYST COMPONENT COMPRISING TITANIUM, MAGNESIUM, HALOGEN AND A 1,3-DIETHER, ORGANIC ALUMINUM COMPOUND, ORGANIC SILICON COMPOUND CHINA PETRO - CHEMICAL CORPORATION (CN) 2004-01-27 US claimed
EP-1260523-A1 CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS CHINA PETROCHEMICAL CORPORATION (CN) 2002-11-27 EP claimed
US-20010025006-A1 Catalyst system for the (co) polymerization of olefins BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, SINOPEC (CN) 2001-09-27 US claimed
EP-0728769-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1998-08-19 EP claimed
EP-0728724-A1 Diethers suitable for use in the preparation of Ziegler-Natta catalysts MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP claimed
EP-0728769-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP claimed
US-10954324-B2 Catalyst component for high activity and high stereoselectivity in olefin polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2021-03-23 US disclosed
US-10364305-B2 Polyolefin and a process for preparing the same RELIANCE INDUSTRIES LIMITED (IN) 2019-07-30 US disclosed
US-10308563-B2 Process for producing ethylene oligomers HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2019-06-04 US disclosed
EP-0728770-A1 Process for the preparation of solid catalyst components for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP disclosed
EP-0728724-A1 Diethers suitable for use in the preparation of Ziegler-Natta catalysts MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP disclosed
EP-0728769-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308563-B2 Process for producing ethylene oligomers OXER1, HAO2, ORC3 PDK2 2196/4885CNR2 305/4885NPSR1 2694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.