Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301024 | 0.90 | — | — | |
| SCHEMBL672141 | 0.90 | KDM5A (0.47) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL8920891 | 0.90 | KDM5A (0.47) | KDM5APHF8KDM2AKDM4CKDM7A | |
| Water SCHEMBL15822499 | 0.87 | KDM5A (0.46) | KDM5APHF8KDM2AKDM4CKDM7A | |
| Hydrochloric Acid SCHEMBL8026839 | 0.87 | — | — | |
| Bromide SCHEMBL15821114 | 0.87 | KDM5A (0.46) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL2232212 | 0.86 | KDM5A (0.36) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL28622817 | 0.86 | KDM5A (0.47) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL28064583 | 0.83 | HPGD (0.36) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL9860342 | 0.83 | KDM5A (0.57) | KDM5APHF8KDM2AKDM4CKDM7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110018540-B | Stretched film and method for producing same | 柯尼卡美能达株式会社 | 2022-06-14 | — | — | CN | disclosed |
| CN-110014679-B | Method for producing stretched film | 柯尼卡美能达株式会社 | 2021-09-14 | — | — | CN | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| CN-101356156-B | Aspartic protease inhibitors | VITAE PHARMACEUTICALS INC | 2012-12-05 | — | — | CN | disclosed |
| CN-100443458-C | Stereoselective synthesis of a 4,4-disubstituted cyclohexanepropanoic acid | MERCK SHARP & DOHME (GB) | 2008-12-17 | — | — | CN | disclosed |
| US-7411088-B2 | Stereoselective synthesis of a 4,4-disubstituted cyclohexanepropanoic acid | MERCK & CO., INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-20070225520-A1 | Stereoselective Synthesis of a 4,4-Disubstituted Cyclohexanepropanoic Acid | MERCK SHARP & DOHME LLC | 2007-09-27 | — | — | US | disclosed |
| EP-1718593-B1 | STEREOSELECTIVE SYNTHESIS OF A 4,4-DISUBSTITUTED CYCLOHEXANEPROPANOIC ACID | MERCK SHARP & DOHME (GB) | 2007-07-25 | — | — | EP | disclosed |
| CN-1918106-A | Stereoselective synthesis of a 4,4-disubstituted cyclohexanepropanoic acid | MERCK SHARP & DOHME (GB) | 2007-02-21 | — | — | CN | disclosed |
| EP-1718593-A1 | STEREOSELECTIVE SYNTHESIS OF A 4,4-DISUBSTITUTED CYCLOHEXANEPROPANOIC ACID | MERCK SHARP & DOHME LTD. (GB) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005080309-A1 | STEREOSELECTIVE SYNTHESIS OF A 4,4-DISUBSTITUTED CYCLOHEXANEPROPANOIC ACID | MERCK SHARP & DOHME LIMITED (GB) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225520-A1 | Stereoselective Synthesis of a 4,4-Disubstituted Cyclohexanepropanoic Acid | AR, SRD5A2, SRD5A1 | KDM5A 2104/4885PHF8 1865/4885KDM2A 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.