Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401679 | 0.89 | HPGD (0.41) | HPGDTP53KDM5AKDM7AKDM4C | |
| SCHEMBL5083120 | 0.83 | KDM5A (0.42) | HPGDEPHX2KDM5AKDM7AKDM4C | |
| SCHEMBL17335681 | 0.81 | HSD11B1 (0.38) | HPGDEPHX2TP53KDM5AKDM7A | |
| SCHEMBL15881507 | 0.81 | HSD11B1 (0.38) | HPGDEPHX2TP53KDM5AKDM7A | |
| SCHEMBL24722823 | 0.81 | ALDH1A1 (0.39) | HPGDEPHX2TP53MAPTHSD11B1 | |
| SCHEMBL27940250 | 0.79 | HPGD (0.54) | HPGDTP53MAPTHSD11B1ALDH1A1 | |
| SCHEMBL149054 | 0.78 | TSHR (0.41) | EPHX2TSHRSHBG | |
| SCHEMBL10576267 | 0.78 | TSHR (0.41) | EPHX2TSHRSHBG | |
| SCHEMBL11670009 | 0.77 | HPGD (0.57) | HPGDTP53MAPTHSD11B1ALDH1A1 | |
| SCHEMBL1188266 | 0.76 | TSHR (0.46) | HPGDEPHX2MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658628-A | Novel arylalkene derivatives and use thereof as selective estrogen receptor modulators | 北京赛林泰医药技术有限公司 | 2016-06-08 | — | — | CN | disclosed |