Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 5/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3321601 | 1.00 | LMNA (0.46) | LMNAFAAHCNR1CNR2SPHK1 | |
| SCHEMBL16712169 | 1.00 | LMNA (0.46) | LMNAFAAHCNR1CNR2SPHK1 | |
| SCHEMBL28778969 | 1.00 | LMNA (0.46) | LMNAFAAHCNR1CNR2SPHK1 | |
| SCHEMBL30692694 | 0.91 | ALDH1A1 (0.39) | LMNAFAAHCNR1CNR2DNM1 | |
| SCHEMBL27627092 | 0.91 | ALDH1A1 (0.39) | LMNAFAAHCNR1CNR2DNM1 | |
| SCHEMBL2767818 | 0.87 | LMNA (0.46) | LMNAFAAHCNR1CNR2SPHK1 | |
| SCHEMBL28770782 | 0.82 | LMNA (0.44) | LMNAFAAHCNR1CNR2SPHK1 | |
| SCHEMBL29100357 | 0.82 | LMNA (0.44) | LMNAFAAHCNR1CNR2SPHK1 | |
| SCHEMBL28984207 | 0.81 | — | — | |
| SCHEMBL31174518 | 0.80 | LMNA (0.43) | LMNASPHK1DNM1SMPD1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486533-B1 | USE OF A POLYESTER RESIN COMPOSITION FOR PROFILE EXTRUSION MOLDING | TOYO BOSEKI (JP) | 2008-07-30 | — | — | EP | disclosed |
| US-20060217495-A1 | Polyester resin composition for profile extrusion molding and molded article comprising the same | TOYO BOSEKI KABUSHIKI KAISHA | 2006-09-28 | — | — | US | disclosed |
| US-7084214-B2 | Mixture of amorphous and crystalline polyestrer with nucleation agent | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2006-08-01 | — | — | US | disclosed |
| EP-1486533-A1 | POLYESTER RESIN COMPOSITIONS FOR PROFILE EXTRUSION AND PROFILES MADE THEREFROM | Toyo Boseki Kabushiki Kaisha (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-20040010073-A1 | Polyester resin composition for profile extrusion molding and molded article comprising the same | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2004-01-15 | — | — | US | disclosed |