Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722708 | 0.95 | LTA4H (0.40) | SOAT1LTA4HFAAHMGLLABCB1 | |
| SCHEMBL4724824 | 0.91 | MAPT (0.34) | BCHEACHECYP1A2CYP2C19 | |
| SCHEMBL4721792 | 0.84 | KDM4E (0.41) | LTA4H | |
| SCHEMBL5083212 | 0.77 | SOAT1 (0.41) | SOAT1LTA4HFAAHMGLLPTPN1 | |
| SCHEMBL4767264 | 0.76 | TSHR (0.38) | — | |
| SCHEMBL4722707 | 0.72 | CYP2C9 (0.41) | SOAT1LTA4HFAAHMGLLABCB1 | |
| SCHEMBL4724823 | 0.67 | ALDH1A1 (0.37) | ABCB1BCHEACHECYP1A2CYP19A1 | |
| SCHEMBL558587 | 0.67 | BRD4 (0.42) | — | |
| Biphenyl SCHEMBL3197075 | 0.66 | LTA4H (0.52) | SOAT1LTA4HPTPN1CNR2 | |
| SCHEMBL4765647 | 0.66 | CYP2C9 (0.46) | LTA4HPTPN1BCHEACHECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375081-B2 | Therapeutic combination of a pneumocandin derivative and an antifungal agent | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |
| US-6875740-B1 | Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-04-05 | — | — | US | claimed |