SCHEMBL5083286

SCHEMBL5083286

C=CCOc1c(C)cc(C(=C)C)cc1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.36
PTGS2 P35354 3/20 0.36
HSD17B10 Q99714 1/20 0.35
MAPT P10636 3/20 0.35
LMNA P02545 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 2/20 0.34
KDM4E B2RXH2 2/20 0.34
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
TLR4 O00206 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14845471 0.81 KDM4E (0.38) PTGS1PTGS2HSD17B10MAPTLMNA
SCHEMBL262782 0.81 SMN1; SMN2 (0.43) PTGS1PTGS2MAPTLMNASMN1; SMN2
Hydrochloric Acid SCHEMBL261292 0.79 SMN1; SMN2 (0.43) PTGS1PTGS2MAPTLMNASMN1; SMN2
SCHEMBL4096065 0.79 TSHR (0.44) PTGS1PTGS2LMNASMN1; SMN2KDM4E
SCHEMBL261291 0.79 KDM4E (0.38) PTGS1PTGS2HSD17B10MAPTLMNA
SCHEMBL8161008 0.79 POLB (0.39) PTGS1PTGS2HSD17B10MAPTLMNA
SCHEMBL472102 0.79 PTGS1 (0.38) PTGS1PTGS2HSD17B10MAPTLMNA
SCHEMBL26926134 0.78 LMNA (0.44) PTGS1PTGS2HSD17B10MAPTLMNA
SCHEMBL262849 0.77 KDM4E (0.44) HSD17B10MAPTLMNASMN1; SMN2GAA
SCHEMBL20543421 0.77 KDM4E (0.37) PTGS1PTGS2MAPTSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4458898-A1 POLYETHYLENE BLEND COMPOSITION Dow Global Technologies Llc (US) 2024-11-06 EP claimed
US-12116463-B2 Masterbatch with semi-crystalline polyolefin carrier resin DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-15 US claimed
US-11952470-B2 Masterbatch with semi-crystalline polyolefin carrier resin DOW GLOBAL TECHNOLOGIES LLC (US) 2024-04-09 US claimed
US-20230151162-A1 MASTERBATCH WITH SEMI-CRYSTALLINE POLYOLEFIN CARRIER RESIN DOW GLOBAL TECHNOLOGIES LLC (US) 2023-05-18 US claimed
US-20210079176-A1 MASTERBATCH WITH SEMI-CRYSTALLINE POLYOLEFIN CARRIER RESIN DOWN GLOBAL TECH LLC (US) 2021-03-18 US claimed
US-20210079177-A1 MASTERBATCH WITH SEMI-CRYSTALLINE POLYOLEFIN CARRIER RESIN DOW CHEMICAL (CHINA) INVESTMENT COMPANY LIMITED (CN) 2021-03-18 US claimed
US-20200148865-A1 POLYETHYLENE BLEND COMPOSITION DOW GLOBAL TECHNOLOGIES LLC 2020-05-14 US claimed
EP-3615608-A1 POLYETHYLENE BLEND COMPOSITION Dow Global Technologies LLC (US) 2020-03-04 EP claimed
WO-2018200319-A1 POLYETHYLENE BLEND COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-01 WO claimed
US-6277925-B1 COMPRISING A CURABLE POLYMER, AN ORGANIC PEROXIDE INITIATOR, AND AN ALLYL COMPOUND AS SCORCH RETARDER HERCULES INCORPORATED 2001-08-21 US claimed
WO-2000055226-A1 ALLYL COMPOUNDS, COMPOSITIONS CONTAINING ALLYL COMPOUNDS AND PROCESSES FOR FORMING AND CURING POLYMER COMPOSITIONS HERCULES INCORPORATED (US) 2000-09-21 WO claimed
US-12441868-B2 Polyolefin formulation Dow Global Technlogies LLC (US) 2025-10-14 US disclosed
EP-3814419-B1 POLYOLEFIN FORMULATION WITH POLY (2-ALKYL-2-OXAZOLINE) DOW GLOBAL TECHNOLOGIES LLC (US) 2025-05-14 EP disclosed
US-12293857-B2 Composite of non-polar organic polymer, polar organic polymer, and ultra-low-wettability carbon black DOW GLOBAL TECHNOLOGIES LLC (US) 2025-05-06 US disclosed
US-12269960-B2 Polyolefin composition DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-08 US disclosed
WO-2018200319-A1 POLYETHYLENE BLEND COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-01 WO disclosed
EP-1564231-B1 Process for the production of a polyolefin modified with a polar monomer IND POLIECO M P B SRL (IT) 2008-12-24 EP disclosed
EP-1564231-A1 Process for the production of a polyolefin modified with a polar monomer Industrie Polieco - M.P.B. Srl (IT) 2005-08-17 EP disclosed
US-6277925-B1 COMPRISING A CURABLE POLYMER, AN ORGANIC PEROXIDE INITIATOR, AND AN ALLYL COMPOUND AS SCORCH RETARDER HERCULES INCORPORATED 2001-08-21 US disclosed
WO-2000055226-A1 ALLYL COMPOUNDS, COMPOSITIONS CONTAINING ALLYL COMPOUNDS AND PROCESSES FOR FORMING AND CURING POLYMER COMPOSITIONS HERCULES INCORPORATED (US) 2000-09-21 WO disclosed