SCHEMBL5083309

SCHEMBL5083309

C=CC(=O)C(CCC)[SiH](OC)OC

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
HPGD P15428 1/20 0.32
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.31
CHRM1 P11229 1/20 0.30
AKR1A1 P14550 1/20 0.30
CHRM3 P20309 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30
HRH1 P35367 1/20 0.30
DRD3 P35462 1/20 0.30
SLC6A3 Q01959 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28384140 0.85 TSHR (0.33) TSHRHPGDALDH1A1
SCHEMBL193209 0.71 TSHR (0.38) TSHRHPGDALDH1A1THRB
SCHEMBL8079206 0.69 TSHR (0.40) TSHRHPGDALDH1A1THRBCHRM1
SCHEMBL8743001 0.69 HDAC1 (0.50) TSHRHPGDALDH1A1CHRM1AKR1A1
SCHEMBL12468677 0.68 TSHR (0.39) TSHRHPGDTHRB
SCHEMBL28419200 0.68 TSHR (0.32) TSHRALDH1A1
SCHEMBL9575274 0.67
SCHEMBL4790077 0.67
SCHEMBL1056648 0.67
SCHEMBL6151934 0.66 TSHR (0.56) TSHRHPGDALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025023073-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, AND DISPLAY DEVICE PROVIDED THEREWITH 東レ株式会社 2025-01-30 WO disclosed
CN-110662805-B Silicone resin composition, adhesive using same, display device, semiconductor device, and lighting device 东丽株式会社 2022-02-08 CN disclosed
CN-113491636-A Dental composition characterized by index of amount of silane coupling agent blended 株式会社松风 2021-10-12 CN disclosed
CN-111373325-A Silicone resin composition, cured film, and display device 东丽株式会社 2020-07-03 CN disclosed
CN-110662805-A Silicone resin composition, adhesive using same, display device, semiconductor device, and lighting device 东丽株式会社 2020-01-07 CN disclosed
EP-1997842-A2 Process for the preparation of urethane resins and urethan resin compositions KONISHI CO., LTD. (JP) 2008-12-03 EP disclosed