Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082095 | 0.87 | NPC1 (0.49) | TSHRALDH1A1RAB9ATP53ADRB2 | |
| SCHEMBL5085911 | 0.85 | TSHR (0.51) | TSHRALDH1A1RAB9ATP53ADRB2 | |
| SCHEMBL5082889 | 0.83 | PDCD1 (0.54) | TSHRALDH1A1RAB9ATP53ADRB2 | |
| SCHEMBL5082327 | 0.83 | TSHR (0.52) | TSHRALDH1A1RAB9ATP53ADRB2 | |
| SCHEMBL5083523 | 0.83 | ALDH1A1 (0.46) | TSHRALDH1A1RAB9ATP53ADRB2 | |
| SCHEMBL5085942 | 0.81 | ALDH1A1 (0.47) | TSHRALDH1A1RAB9ATP53ADRB2 | |
| SCHEMBL5079860 | 0.81 | TSHR (0.47) | TSHRALDH1A1RAB9ATP53ADRB2 | |
| SCHEMBL5941267 | 0.81 | TSHR (0.56) | TSHRALDH1A1RAB9ATP53PDCD1 | |
| SCHEMBL5082882 | 0.79 | ALDH1A1 (0.45) | TSHRALDH1A1RAB9ATP53ADRB2 | |
| SCHEMBL5082172 | 0.79 | KMT2A (0.46) | TSHRALDH1A1RAB9ATP53ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746110-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF | CHINA PETROLEUM & CHEMICAL (CN) | 2015-03-11 | — | — | EP | disclosed |
| US-7351778-B2 | Catalyst component for olefin polymerization and catalyst comprising the same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-04-01 | — | — | US | disclosed |
| EP-1746110-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF | China Petroleum & Chemical Corporation (CN) | 2007-01-24 | — | — | EP | disclosed |