SCHEMBL5082172

SCHEMBL5082172

CC(C)COC(=O)C(Cc1ccccc1)C(C)OC(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
RAB9A P51151 2/20 0.42
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
TP53 P04637 1/20 0.41
PLA2G1B P04054 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
CTSL P07711 1/20 0.40
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
MDM2 Q00987 1/20 0.40
CYP2D6 P10635 1/20 0.39
CA12 O43570 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5082842 0.88 MMP8 (0.48) KMT2AMEN1ALDH1A1TSHRSLC6A2
SCHEMBL5085942 0.86 ALDH1A1 (0.47) KMT2AMEN1ALDH1A1TSHRTDP1
SCHEMBL5079860 0.86 TSHR (0.47) ALDH1A1TSHRTDP1RAB9AADRB2
SCHEMBL5082867 0.86 KMT2A (0.61) KMT2AMEN1ALDH1A1TSHRSLC6A2
SCHEMBL5083408 0.86 PDCD1 (0.49) KMT2AMEN1ALDH1A1TSHRSLC6A2
SCHEMBL5941353 0.84 TSHR (0.50) KMT2AMEN1ALDH1A1TSHRSLC6A2
SCHEMBL1783041 0.84 ALDH1A1 (0.53) KMT2AMEN1ALDH1A1TSHRRAB9A
SCHEMBL5082882 0.84 ALDH1A1 (0.45) KMT2AMEN1ALDH1A1TSHRRAB9A
SCHEMBL5083433 0.82 MEN1 (0.44) KMT2AMEN1ALDH1A1TSHRTDP1
SCHEMBL5083437 0.82 ALDH1A1 (0.43) ALDH1A1TSHRRAB9AADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746110-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2015-03-11 EP disclosed
CN-101759816-B Method for preparing a catalyst component for olefinic polymerization, and a catalyst component thereof CHINA PETROLEUM & CHEMICAL 2012-05-30 CN disclosed
CN-101759816-A Method for preparing a catalyst component for olefinic polymerization, and a catalyst component thereof CHINA PETROLEUM & CHEMICAL 2010-06-30 CN disclosed
CN-100429242-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2008-10-29 CN disclosed
CN-100429243-C Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2008-10-29 CN disclosed
US-7351778-B2 Catalyst component for olefin polymerization and catalyst comprising the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-04-01 US disclosed
CN-100348624-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2007-11-14 CN disclosed
EP-1746110-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2007-01-24 EP disclosed
CN-1891722-A Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2007-01-10 CN disclosed
CN-1282670-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-11-01 CN disclosed
CN-1803862-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1803863-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1690090-A Catalyst components for olefinic polyreaction and catalyst thereof SINOPEC CORP (CN) 2005-11-02 CN disclosed