Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.70 |
| ▸ | ACP1 | P24666 | 8/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.45 |
| ▸ | PTPN13 | Q12923 | 2/20 | 0.45 |
| ▸ | SSU72 | Q9NP77 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914825 | 0.85 | SRC (0.55) | SRCACP1PTPN1PTPN6PTPN11 | |
| SCHEMBL27829711 | 0.83 | SRC (0.53) | SRCACP1PTPN1PTPN6PTPN11 | |
| SCHEMBL7168498 | 0.83 | SRC (0.53) | SRCACP1PTPN1PTPN6PTPN11 | |
| SCHEMBL20869602 | 0.83 | SRC (1.00) | SRCACP1PTPN1PTPN6PTPN11 | |
| SCHEMBL9912818 | 0.83 | SRC (1.00) | SRCACP1PTPN1PTPN6PTPN11 | |
| SCHEMBL11166146 | 0.83 | SRC (1.00) | SRCACP1PTPN1PTPN6PTPN11 | |
| SCHEMBL28144339 | 0.82 | SRC (0.52) | SRCACP1PTPN1PTPN6PTPN11 | |
| SCHEMBL6408416 | 0.82 | SRC (0.62) | SRCACP1PTPN1PTPN6PTPN11 | |
| SCHEMBL13281779 | 0.82 | SRC (0.52) | SRCACP1PTPN1PTPN6PTPN11 | |
| SCHEMBL27750137 | 0.81 | SRC (0.61) | SRCACP1PTPN1PTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180170861-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES AND USED THEREOF | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2018-06-21 | — | — | US | disclosed |
| EP-1718599-A4 | SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS | EXXONMOBIL RES & ENG CO (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1718599-A1 | SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS | ExxonMobil Research and Engineering Company (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005082835-A1 | SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170861-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES AND USED THEREOF | PTPA, EPM2A, PTPRA | SRC 201/4885ACP1 66/4885PTPN1 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.