SCHEMBL6914825

SCHEMBL6914825

CC(=O)C(c1ccccc1)S(=O)(=O)C(C(C)=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.55
LMNA P02545 3/20 0.43
CYP2D6 P10635 1/20 0.43
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
ACP1 P24666 1/20 0.40
PTPN12 Q05209 1/20 0.40
PTPN1 P18031 1/20 0.40
PTPN6 P29350 1/20 0.40
PTPN11 Q06124 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HSD11B1 P28845 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27829711 0.85 SRC (0.53) SRCLMNACYP2D6HPGDCYP2C19
SCHEMBL5083576 0.85 SRC (0.70) SRCLMNACYP2D6HPGDCYP2C19
SCHEMBL7168498 0.85 SRC (0.53) SRCLMNACYP2D6HPGDCYP2C19
SCHEMBL13281779 0.83 SRC (0.52) SRCLMNACYP2D6HPGDCYP2C19
SCHEMBL28144339 0.83 SRC (0.52) SRCLMNACYP2D6HPGDCYP2C19
SCHEMBL20582610 0.82 SRC (0.50) SRCLMNACYP2D6HPGDCYP2C19
SCHEMBL6204480 0.74 SRC (0.67) SRCLMNACYP2D6CYP2C19MAPK1
SCHEMBL9980574 0.73 SRC (0.46) SRCLMNACYP2D6HPGDMAPK1
SCHEMBL13626301 0.73 SRC (0.46) SRCLMNACYP2D6HPGDMAPK1
SCHEMBL28085685 0.72 SRC (0.64) SRCLMNACYP2D6CYP2C19MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed