Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250224 | 0.98 | ACE2 (0.49) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10498621 | 0.84 | ACE2 (0.41) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL10450295 | 0.82 | CA1 (0.45) | CA1ACE2FFAR1FFAR4GPR84 | |
| SCHEMBL6829832 | 0.81 | CA2 (0.47) | ACE2FFAR1FFAR4GPR84MAPT | |
| SCHEMBL6829829 | 0.81 | CA2 (0.47) | ACE2FFAR1FFAR4GPR84MAPT | |
| SCHEMBL6692423 | 0.81 | CA2 (0.47) | ACE2FFAR1FFAR4GPR84MAPT | |
| SCHEMBL3039825 | 0.80 | CA2 (0.50) | CA1FFAR1GPR84MAPTLCK | |
| SCHEMBL3034502 | 0.80 | CA2 (0.50) | CA1FFAR1GPR84MAPTLCK | |
| SCHEMBL3034500 | 0.80 | CA2 (0.50) | CA1FFAR1GPR84MAPTLCK | |
| SCHEMBL10668577 | 0.79 | CA1 (0.52) | CA1ACE2FFAR1FFAR4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1734940-B1 | COMBINATIONS OF DERAMCICLANE AND OPIOIDS FOR USE AS ANALGESICS | EGIS GYOGYSZERGYAR NYRT (HU) | 2008-10-08 | — | — | EP | claimed |