SCHEMBL50838

SCHEMBL50838

CCOC=C(C(=O)OCC)C(=O)OCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.56
GLO1 Q04760 1/20 0.56
ALDH1A1 P00352 4/20 0.48
CYP2D6 P10635 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
LMNA P02545 4/20 0.43
MAPT P10636 4/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
S1PR4 O95977 1/20 0.43
S1PR1 P21453 1/20 0.43
MAPK1 P28482 1/20 0.43
DHODH Q02127 2/20 0.42
HSD17B10 Q99714 1/20 0.40
GAA P10253 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
PLIN1 O60240 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12660757 0.92 NPSR1 (0.48) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL15945285 0.92 NPSR1 (0.48) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL27110990 0.90 NPSR1 (0.47) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL12180594 0.89 NPSR1 (0.50) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL1186672 0.89 GLO1 (0.67) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL1369380 0.89 NPSR1 (0.50) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL8832099 0.89 NPSR1 (0.50) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL1186674 0.89 GLO1 (0.67) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL4197379 0.89 GLO1 (0.67) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL11742099 0.89 NPSR1 (0.50) NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5549 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111296-A1 ELECTROLYTE COMPOSITIONS AND ELECTROCHEMICAL DEVICES USING THE SAME II-VI DELAWARE, INC. (US) 2025-05-30 WO claimed
CN-111747890-B Preparation method of 4, 7-dichloroquinoline 重庆医药高等专科学校 2025-05-09 CN claimed
CN-115774065-B GC detection method for diethyl ethoxymethylene malonate 武汉海特生物创新医药研究有限公司 2025-04-01 CN claimed
CN-118994183-B Synthesis method of stable isotope labeled oxolinic acid 山东辉璟生物医药科技有限公司 2025-03-11 CN claimed
CN-119306697-A 4-Quinolinone derivative and preparation method and application thereof 山东大学 2025-01-14 CN claimed
US-12172991-B2 Bicycle topoisomerase i inhibiting compounds, process for preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-12-24 US claimed
CN-118160746-B Bactericide for preventing and treating diseases of leaves and fruits and preparation method thereof 潍坊奥丰作物病害防治有限公司 2024-08-02 CN claimed
CN-118160746-A Bactericide for preventing and treating diseases of leaves and fruits and preparation method thereof 潍坊奥丰作物病害防治有限公司 2024-06-11 CN claimed
CN-116200183-B High-efficiency variable-viscosity fracturing fluid for deep coal bed gas development and integrated construction method 四川申和新材料科技有限公司 2024-05-28 CN claimed
EP-4365162-A2 A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE Intervet International B.V. (NL) 2024-05-08 EP claimed
EP-0376870-A1 A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) 1990-07-04 EP claimed
US-4868299-A Antibacterially active pyrido-benzothiazine derivatives with long-term action MEDIOLANUM FARMACEUTICI SRL (IT) 1989-09-19 US claimed
US-4851566-A CONDENSING ALKYL MALONATE WITH ORTHOESTER IN PRESENCE OF CARBOXYLIC ACID AND CADMIUM OR MAGNESIUM COMPOUND CATALYST RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1989-07-25 US claimed
EP-0267432-A1 Antibacterially active pyrido-benzothiazine derivatives with long term action MEDIOLANUM FARMACEUTICI s.r.l. (IT) 1988-05-18 EP claimed
EP-0152319-B1 PROCESS FOR OBTAINING COMPOUNDS WITH AN ALKOXYACYLIDENE GROUP RHONE-POULENC CHIMIE (FR) 1987-07-22 EP claimed
US-4668784-A HALOANILINE WITH POTASSIUM THIOCYANATE MEDIOLANUM FARMACEUTICI S.R.L. (IT) 1987-05-26 US claimed
EP-0165375-A2 Derivative of pyrido-benzothiazine with high anti-microbial activity MEDIOLANUM FARMACEUTICI s.r.l. (IT) 1985-12-27 EP claimed
EP-0155244-A2 1-Ethyl-6-fluoro-7-(1H-pirrol-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid: preparation and antimicrobial activities BIOCHEM DESIGN S.r.l. (IT) 1985-09-18 EP claimed
US-4125720-A Process for the preparation of 4-chloro-5-alkoxycarbonyl-2-methoxy-pyrimidines LABORATOIRE ROGER BELLON (FR) 1978-11-14 US claimed
US-4091040-A Procedure for making trimethylolmethane THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1978-05-23 US claimed