Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1186672 | 1.00 | GLO1 (0.67) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL1186674 | 1.00 | GLO1 (0.67) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL50838 | 0.89 | NPSR1 (0.56) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL24937270 | 0.88 | GLO1 (0.57) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL28786257 | 0.88 | GLO1 (0.57) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL29636860 | 0.88 | GLO1 (0.53) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL11651953 | 0.86 | GLO1 (0.50) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL11651951 | 0.86 | GLO1 (0.50) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL2364222 | 0.85 | GLO1 (0.50) | GLO1NPSR1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL824578 | 0.84 | GLO1 (0.48) | GLO1NPSR1ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619388-A1 | CATHEPSIN L INHIBITORS | Biofront Therapeutics (Beijing) Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| US-20250188040-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS INC | 2025-06-12 | — | — | US | disclosed |
| EP-4551555-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | Vividion Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| US-12264159-B2 | Functionalized heterocycles as antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2025-04-01 | — | — | US | disclosed |
| CN-119677716-A | Pharmaceutical compositions comprising WRN helicase inhibitors | 维维迪恩医疗公司 | 2025-03-21 | — | — | CN | disclosed |
| US-12187685-B2 | Pharmaceutical compositions comprising WRN helicase inhibitors | VIVIDION THERAPEUTICS, INC. | 2025-01-07 | — | — | US | disclosed |
| CN-118515653-B | EZH2 specific inhibitor and preparation method and application thereof | 西湖制药(杭州)有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-115279767-B | Tetracyclic compounds as inhibitors of hepatitis b surface antigen | 正大天晴药业集团股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-118515653-A | EZH2 specific inhibitor and preparation method and application thereof | 西湖制药(杭州)有限公司 | 2024-08-20 | — | — | CN | disclosed |
| US-20240262828-A1 | Functionalized Heterocycles as Antiviral Agents | ENANTA PHARM INC (US) | 2024-08-08 | — | — | US | disclosed |
| EP-1682535-A1 | HETEROARYL DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-26 | — | — | EP | disclosed |
| US-6995263-B2 | Indolyl and dihydroindolyl derivatives, their manufacture and use as pharmaceutical agents | HOFFMANN-LA ROCHE INC. (US) | 2006-02-07 | — | — | US | disclosed |
| WO-2005049606-A1 | HETEROARYL DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-02 | — | — | WO | disclosed |
| US-20050096353-A1 | Indolyl and dihydroindolyl derivatives, their manufacture and use as pharmaceutical agents | HOFFMANN-LA ROCHE INC. | 2005-05-05 | — | — | US | disclosed |
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1439169-A1 | DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-07-21 | — | — | EP | disclosed |
| US-4837238-A | Pharmacologically useful pyrazolopyridines | BEECHAM GROUP P.L.C. (GB) | 1989-06-06 | — | — | US | disclosed |
| EP-0193329-A2 | Pyrazolopyridines, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1986-09-03 | — | — | EP | disclosed |
| US-4167568-A | TREATMENT OF RESPIRATORY SYSTEM DISORDERS, ANTIHISTAMINES | MAY & BAKER LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |
| US-4104049-A | Chlorine-substituted vinylaminobenzoic acid compounds and plant growth regulant compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262828-A1 | Functionalized Heterocycles as Antiviral Agents | HCCS, HAVCR2, HDGF | GLO1 2628/4885NPSR1 1922/4885ALDH1A1 2352/4885 |
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | DDT, WEE1, NOTUM | GLO1 33/4885NPSR1 2069/4885ALDH1A1 875/4885 |
| US-12187685-B2 | Pharmaceutical compositions comprising WRN helicase inhibitors | RECQL, BLM, WRN | GLO1 1439/4885NPSR1 4482/4885ALDH1A1 2371/4885 |
| US-20250188040-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | RECQL, BLM, WRN | GLO1 1439/4885NPSR1 4482/4885ALDH1A1 2371/4885 |
| US-20050096353-A1 | Indolyl and dihydroindolyl derivatives, their manufacture and use as pharmaceutical agents | PPARD, PPARA, PPARG | GLO1 4095/4885NPSR1 510/4885ALDH1A1 788/4885 |
| US-12264159-B2 | Functionalized heterocycles as antiviral agents | HCCS, HAVCR2, HDGF | GLO1 2628/4885NPSR1 1922/4885ALDH1A1 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.