SCHEMBL508419

SCHEMBL508419

O=C(O)CCOCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
KEAP1 Q14145 1/20 0.54
FOLH1 Q04609 1/20 0.53
FFAR1 O14842 4/20 0.51
FFAR4 Q5NUL3 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.50
HTT P42858 2/20 0.50
MAPK1 P28482 2/20 0.50
SLC6A3 Q01959 2/20 0.50
HDAC3 O15379 1/20 0.50
ADRA1A P35348 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4589727 0.98 TSHR (0.54) TSHRKEAP1FOLH1FFAR1FFAR4
SCHEMBL25358736 0.96 TSHR (0.52) TSHRKEAP1FOLH1FFAR1FFAR4
SCHEMBL24435524 0.96 TSHR (0.52) TSHRKEAP1FOLH1FFAR1FFAR4
SCHEMBL24207916 0.96 TSHR (0.52) TSHRKEAP1FOLH1FFAR1FFAR4
SCHEMBL26679505 0.89 FOLH1 (0.49) TSHRKEAP1FOLH1FFAR1FFAR4
SCHEMBL291194 0.88 SMN1; SMN2 (0.57) TSHRKEAP1FOLH1FFAR1FFAR4
SCHEMBL7708032 0.88 TSHR (0.56) TSHRKEAP1FOLH1SMN1; SMN2HTT
SCHEMBL712393 0.86 MAPT (0.56) TSHRKEAP1FOLH1FFAR1FFAR4
SCHEMBL24756824 0.85 SMN1; SMN2 (0.53) TSHRKEAP1FOLH1FFAR1FFAR4
SCHEMBL22367410 0.85 SMN1; SMN2 (0.53) TSHRKEAP1FOLH1FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023205458-A2 FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-26 WO claimed
CN-110204522-B Preparation method of 5, 6-dihydro-2H-pyran-2-one 南京焕然生物科技有限公司 2022-04-05 CN claimed
CN-110204522-A A kind of preparation method of 5,6- dihydro -2H- pyran-2-one 南京焕然生物科技有限公司 2019-09-06 CN claimed
US-8383637-B2 2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE) JANSSSEN PHARMACEUTICA N.V. (BE) 2013-02-26 US claimed
EP-1776349-B1 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) JANSSEN PHARMACEUTICA NV (BE) 2010-10-06 EP claimed
EP-1776349-A2 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) JANSSEN PHARMACEUTICA N.V. (BE) 2007-04-25 EP claimed
US-20060079687-A1 Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) JANSSEN PHARMACEUTICA, N.V. (BE) 2006-04-13 US claimed
WO-2006017836-A2 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) JANSSEN PHARMACEUTICA, N.V. (BE) 2006-02-16 WO claimed
EP-1569925-A1 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2005-09-07 EP claimed
WO-2004055003-A1 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2004-07-01 WO claimed
CN-1307558-A Process for preparing 4-carboxy-5, 8, 11-tris (carboxymethyl) -1-phenyl-2-oxa-5, 8, 11-triazatridecane-13-oic acid BRACCO IMAGING SPA (IT) 2001-08-08 CN claimed
US-20260146046-A1 BICYCLIC FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2026-05-28 US disclosed
CN-122094963-A Cardioprotective lipids and methods of use 2026-05-26 CN disclosed
WO-2026107328-A1 AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS SEPTERNA, INC. (US) 2026-05-21 WO disclosed
EP-4743174-A1 MODULATORS OF CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY Aconcagua Bio, Inc. (US) 2026-05-20 EP disclosed
US-4529732-A Analgesics PFIZER INC. (US) 1985-07-16 US disclosed
EP-0119087-A1 2-(2-Hydroxy-4-(substituted) phenyl) piperidines PFIZER INC. (US) 1984-09-19 EP disclosed
EP-0093915-A1 Novel beta-lactam derivatives GRUPPO LEPETIT S.P.A. (IT) 1983-11-16 EP disclosed
EP-0060416-A1 New beta-lactam acetic acid derivatives, the process for preparing them, and their use as intermediates for 1-azabicyclo(3.2.0.)hept-2-ene antibiotics GRUPPO LEPETIT S.P.A. (IT) 1982-09-22 EP disclosed
US-4205174-A Process for the production of 6-substituted 4-methyl-2-pyridones LONZA, LTD. (CH) 1980-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146046-A1 BICYCLIC FERROPORTIN INHIBITORS SLC40A1, HAMP, SLC7A1 TSHR 410/4885KEAP1 108/4885FOLH1 1084/4885
US-20060079687-A1 Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) BACE2, BACE1, APP TSHR 4868/4885KEAP1 233/4885FOLH1 705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.