Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KAT2A | Q92830 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081340 | 0.77 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1KMT2ALMNAPOLB | |
| SCHEMBL10396183 | 0.70 | GRM8 (0.32) | ALDH1A1ESR1MEN1KMT2AMAPT | |
| SCHEMBL9049885 | 0.70 | ALDH1A1 (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL9049892 | 0.70 | ALDH1A1 (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL19927564 | 0.68 | CRBN (0.32) | CRBNMEN1KMT2ALMNA | |
| SCHEMBL190832 | 0.68 | TLR4 (0.34) | ALDH1A1KMT2AAPLNR | |
| SCHEMBL13260311 | 0.67 | — | — | |
| SCHEMBL2350098 | 0.67 | — | — | |
| SCHEMBL2352203 | 0.65 | SMN1; SMN2 (0.38) | SMN1; SMN2CRBN | |
| SCHEMBL14593761 | 0.65 | SMN1; SMN2 (0.38) | SMN1; SMN2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912936-A2 | STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS | Pharmacia & Upjohn Company LLC (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2007010387-A2 | STEREOSELECTIVE SYNTHESIS OF 3,4-DISUBSTITUTED CYCLOPENTANONES AND RELATED COMPOUNDS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-25 | — | — | WO | claimed |