Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729414 | 0.79 | GRM2 (0.33) | GRM8GRM6GRM2GRM3 | |
| SCHEMBL14635952 | 0.75 | HSD11B1 (0.31) | — | |
| SCHEMBL1879279 | 0.71 | CYP2C19 (0.35) | GRM8GRM6GRM2GRM3CYP2C19 | |
| SCHEMBL4611943 | 0.67 | — | — | |
| SCHEMBL9729321 | 0.66 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9729328 | 0.66 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19927564 | 0.66 | CRBN (0.32) | CYP2C19MEN1KMT2A | |
| SCHEMBL775170 | 0.65 | TRIM24 (0.32) | GRM8GRM6GRM2GRM3CYP2C19 | |
| SCHEMBL1415539 | 0.65 | GRM8 (0.39) | GRM8GRM6GRM2GRM3CYP2C19 | |
| SCHEMBL3464997 | 0.63 | POLB (0.39) | GRM8GRM6GRM2GRM3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960907-A | Partially saponifying; delarboxylating diesters; optional ketalization | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |