SCHEMBL5084532

SCHEMBL5084532

C=C(C)C(=O)O[Si](CC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
THRB P10828 1/20 0.39
TSHR P16473 3/20 0.38
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2043794 0.83 ALDH1A1 (0.43) ALDH1A1THRBTSHR
SCHEMBL15514061 0.81 THRB (0.42) ALDH1A1THRBTSHR
SCHEMBL3111019 0.80 TSHR (0.46) ALDH1A1THRBTSHR
SCHEMBL28765650 0.80 ALDH1A1 (0.37) ALDH1A1THRBTSHR
SCHEMBL23529413 0.79 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL5940390 0.79 ALDH1A1 (0.38) ALDH1A1THRBTSHR
SCHEMBL4649747 0.79 THRB (0.42) ALDH1A1THRBTSHR
SCHEMBL27530085 0.78 TDP1 (0.52) ALDH1A1THRBTSHR
SCHEMBL28832995 0.77 THRB (0.49) ALDH1A1THRBTSHR
SCHEMBL28664314 0.77 TSHR (0.51) ALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399692-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-12-14 US disclosed
US-11795505-B2 Nucleic acid delivery scaffolds Singular Genomics Systems, Inc. (US) 2023-10-24 US disclosed
US-20230287491-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-09-14 US disclosed
US-20230203579-A1 NANOARRAYS AND METHODS OF USE THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-06-29 US disclosed
CN-103748128-A Cross-linkable materials based on organyl oxysilane-terminated polymers WACKER CHEMIE AG 2014-04-23 CN disclosed
CN-103649150-A Polyurea coatings containing silane PPG IND OHIO INC 2014-03-19 CN disclosed
CN-102634025-A Aqueous silane systems based on bis(trialkoxysilylalkyl)amines EVONIK DEGUSSA GMBH 2012-08-15 CN disclosed
CN-101376710-B Aqueous silane systems based on bis (trialkoxysilylalkyl) amines EVONIK DEGUSSA GMBH 2012-08-08 CN disclosed
CN-101376710-A Aqueous silane systems based on bis (trialkoxysilylalkyl) amines EVONIK DEGUSSA GMBH (DE) 2009-03-04 CN disclosed
EP-1493776-B1 Polycarbonate resin composition GEN ELECTRIC (US) 2008-03-12 EP disclosed
EP-1493776-A2 Polycarbonate resin composition GENERAL ELECTRIC COMPANY (US) 2005-01-05 EP disclosed
EP-1141114-B1 POLYCARBONATE RESIN COMPOSITION GEN ELECTRIC (US) 2004-10-06 EP disclosed
US-6613820-B2 A blend comprising polycarbonate, a styrene copolymer, and a phosphoric ester compound; molding material for high moisture resistance, flame resistant, mechanical strength GENERAL ELECTRIC COMPANY 2003-09-02 US disclosed
US-20020165300-A1 POLYCARBONATE RESIN COMPOSITION CITIBANK, N.A., AS COLLATERAL AGENT 2002-11-07 US disclosed
EP-1141114-A1 POLYCARBONATE RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2001-10-10 EP disclosed
WO-2000039210-A1 POLYCARBONATE RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2000-07-06 WO disclosed