Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8372133 | 0.99 | NPC1 (0.61) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL31267541 | 0.88 | NPC1 (0.66) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL29494818 | 0.88 | NPC1 (0.66) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL258759 | 0.88 | NPC1 (0.66) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL2146554 | 0.87 | NPC1 (0.64) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL10061927 | 0.87 | NPC1 (0.64) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL9408827 | 0.86 | NPC1 (0.50) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL2146562 | 0.85 | NPC1 (0.67) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL9408785 | 0.85 | NPC1 (0.52) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL13288139 | 0.84 | NPC1 (0.61) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593936-A1 | N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-27 | — | — | EP | claimed |
| US-5096977-A | Anhydride polymers | ATOCHEM NORTH AMERICA, INC. (US) | 1992-03-17 | — | — | US | claimed |
| CN-104871036-B | Method for making improved UV-absorbing ophthalmic lenses | 诺华股份有限公司 | 2019-12-10 | — | — | CN | disclosed |
| EP-3542193-A1 | METHOD FOR MAKING OPHTHALMIC LENSES | Novartis AG (CH) | 2019-09-25 | — | — | EP | disclosed |
| US-10338408-B2 | Method for making improved UV-absorbing ophthalmic lenses | NOVARTIS AG (CH) | 2019-07-02 | — | — | US | disclosed |
| US-20180141293-A1 | METHOD FOR MAKING OPHTHALMIC LENSES | ALCON INC. (CH) | 2018-05-24 | — | — | US | disclosed |
| EP-2598936-B1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES | NOVARTIS AG (CH) | 2017-11-01 | — | — | EP | disclosed |
| EP-2932314-B1 | METHOD FOR MAKING IMPROVED UV-ABSORBING OPHTHALMIC LENSES | NOVARTIS AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| EP-2766750-B1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES BY COATING | NOVARTIS AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2932314-A1 | METHOD FOR MAKING IMPROVED UV-ABSORBING OPHTHALMIC LENSES | Novartis AG (CH) | 2015-10-21 | — | — | EP | disclosed |
| US-9052439-B2 | Method for making UV-absorbing ophthalmic lenses | NOVARTIS AG (CH) | 2015-06-09 | — | — | US | disclosed |
| US-4981915-A | HYDRAZIDE MODIFIERS | ATOCHEM NORTH AMERICA, INC. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4981914-A | HYDRAZIDE MODIFIERS | ATOCHEM NORTH AMERICA, INC. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4980420-A | Benzotriazole and oxanilide UV absorber hydrazides | ATOCHEM NORTH AMERICA, INC. (US) | 1990-12-25 | — | — | US | disclosed |
| US-4952664-A | Process for producing weather-resistant polycarbonate with triazine-imide chain terminator | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-08-28 | — | — | US | disclosed |
| US-4874803-A | HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY | PENNWALT CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |
| US-4868246-A | PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS | PENNWALT CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |
| US-4863999-A | IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS | PENNWALT CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0308886-A2 | Dianhydride coupled polymer stabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1989-03-29 | — | — | EP | disclosed |
| EP-0303986-A2 | Multipurpose polymer bound stabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-22 | — | — | EP | disclosed |