Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931516 | 0.76 | KDM4E (0.52) | MAPTKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL5223625 | 0.75 | TRPV1 (0.38) | — | |
| SCHEMBL28617150 | 0.69 | GAA (0.46) | MAPTKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL5177718 | 0.68 | PPARG (0.53) | KMT2AMEN1PPARGPPARASMN1; SMN2 | |
| SCHEMBL5178622 | 0.65 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL3929061 | 0.65 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL3594215 | 0.65 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL3594213 | 0.65 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL19154714 | 0.64 | POLB (0.37) | MAPTKDM4EALDH1A1GAAPOLB | |
| SCHEMBL6772721 | 0.64 | GAA (0.58) | MAPTKDM4EALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893583-A1 | SUBSTITUTED ARYLOXY-N-BICYCLOMETHYL ACETAMIDE COMPOUNDS AS VR1 ANTAGONISTS | Pfizer, Inc. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2006129164-A1 | SUBSTITUTED ARYLOXY-N-BICYCLOMETHYL ACETAMIDE COMPOUNDS AS VR1 ANTAGONISTS | PFIZER JAPAN INC. (JP) | 2006-12-07 | — | — | WO | claimed |