SCHEMBL5084764

SCHEMBL5084764

Cc1ccc(C)c2c1C=CC2C[SiH2]CC1C=Cc2c(C)ccc(C)c21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4600169 0.82
SCHEMBL4629519 0.82
SCHEMBL3677359 0.78 NFKB1 (0.30)
SCHEMBL3619462 0.77
SCHEMBL4599778 0.75
SCHEMBL7759954 0.74 PTGS1 (0.33)
SCHEMBL7101782 0.70
SCHEMBL16405681 0.68
SCHEMBL6453476 0.67
SCHEMBL6461774 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8969482-B2 Dynamic modulation of metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US claimed
EP-2760895-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS Exxon-Mobil Chemical Patents Inc. (US) 2014-08-06 EP claimed
WO-2013048848-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 WO claimed
US-20130085232-A1 Dynamic Modulation of Metallocene Catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 US claimed
US-8969482-B2 Dynamic modulation of metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US disclosed
EP-2760895-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS Exxon-Mobil Chemical Patents Inc. (US) 2014-08-06 EP disclosed
US-20130085232-A1 Dynamic Modulation of Metallocene Catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 US disclosed
WO-2013048848-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 WO disclosed
EP-1954724-A1 SYNDIOTACTIC PROPYLENE ELASTOMERS ExxonMobil Chemical Patents Inc. (US) 2008-08-13 EP disclosed
WO-2007061525-A1 SYNDIOTACTIC PROPYLENE ELASTOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-31 WO disclosed
EP-1753796-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2007-02-21 EP disclosed
WO-2005113622-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-12-01 WO disclosed