⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759954 | 0.86 | PTGS1 (0.33) | — | |
| SCHEMBL28510811 | 0.75 | HTR6 (0.35) | — | |
| SCHEMBL4600169 | 0.70 | — | — | |
| SCHEMBL4629519 | 0.70 | — | — | |
| SCHEMBL5084764 | 0.70 | — | — | |
| SCHEMBL15815573 | 0.70 | SLC6A2 (0.32) | — | |
| SCHEMBL2961491 | 0.69 | CYSLTR2 (0.33) | — | |
| SCHEMBL4599778 | 0.68 | — | — | |
| SCHEMBL3677359 | 0.68 | NFKB1 (0.30) | — | |
| SCHEMBL7759390 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955304-B1 | Bridged metallocene complexes for the (co)polymerization of olefins | POLIMERI EUROPA SPA (IT) | 2003-09-03 | — | — | EP | disclosed |
| US-6417418-B2 | SUCH AS 1,3-PROPENYLIDENE-(1-INDENYL)2 ZIRCONIUM DICHLORIDE; HIGH ACTIVITY, MAKES HIGH MOLECULAR WEIGHT POLYMERS | ENICHEM S.P.A. (IT) | 2002-07-09 | — | — | US | disclosed |
| US-20010031885-A1 | Bridged metallocene complex for the (co) polymerization of olefins | ENICHEM S.P.A. (IT) | 2001-10-18 | — | — | US | disclosed |
| US-6211110-B1 | Bridged metallocene complex for the (co)polymerization of olefins | ENICHEM S.P.A. (IT) | 2001-04-03 | — | — | US | disclosed |
| EP-0955304-A2 | Bridged metallocene complex for the (co)polymerization of olefins | Enichem S.p.A. (IT) | 1999-11-10 | — | — | EP | disclosed |