Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL11629953 | 0.88 | TSHR (0.40) | TSHRALDH1A1AKR1C3THRB | |
| SCHEMBL4356603 | 0.86 | TSHR (0.53) | TSHRALDH1A1 | |
| Styrene SCHEMBL8106691 | 0.85 | MEN1 (0.40) | TSHRALDH1A1AKR1C3MEN1KMT2A | |
| Styrene SCHEMBL194521 | 0.84 | ALDH1A1 (0.43) | TSHRALDH1A1AKR1C3MEN1KMT2A | |
| Styrene SCHEMBL3343449 | 0.84 | AKR1C3 (0.41) | TSHRALDH1A1AKR1C3TAS1R3TAS1R1 | |
| Styrene SCHEMBL8681115 | 0.83 | MEN1 (0.42) | ALDH1A1AKR1C3MEN1KMT2AKDM4E | |
| SCHEMBL15511028 | 0.83 | TSHR (0.47) | TSHRALDH1A1KDM4ETHRB | |
| Styrene SCHEMBL5444349 | 0.82 | KDM4E (0.43) | TSHRALDH1A1AKR1C3MEN1KMT2A | |
| Styrene SCHEMBL5087477 | 0.82 | TSHR (0.58) | TSHRALDH1A1AKR1C3TAS1R3TAS1R1 | |
| Styrene SCHEMBL5221133 | 0.82 | TSHR (0.62) | TSHRALDH1A1TAS1R3TAS1R1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858982-B1 | SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT | DOW CORNING (US) | 2008-08-27 | — | — | EP | claimed |