Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072500 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL5092684 | 0.94 | TSHR (0.32) | TSHR | |
| Iodide SCHEMBL5085184 | 0.94 | TSHR (0.32) | TSHR | |
| Bromide SCHEMBL8723511 | 0.84 | DNM1 (0.35) | TSHR | |
| SCHEMBL1236935 | 0.81 | DNM1 (0.36) | TSHR | |
| Bromide SCHEMBL5138463 | 0.80 | OPRM1 (0.41) | TSHR | |
| Bromide SCHEMBL5086784 | 0.80 | OPRM1 (0.41) | TSHR | |
| Bromide SCHEMBL5089312 | 0.80 | OPRM1 (0.41) | TSHR | |
| Bromide SCHEMBL5092379 | 0.80 | OPRM1 (0.41) | TSHR | |
| Bromide SCHEMBL5350701 | 0.80 | OPRM1 (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |