Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 10/20 | 0.65 |
| ▸ | CES1 | P23141 | 10/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23973483 | 0.82 | CES2 (0.46) | CES2CES1LMNAMAPK1 | |
| SCHEMBL1668558 | 0.82 | CES2 (0.66) | CES2CES1LMNAMAPK1POLB | |
| SCHEMBL1668559 | 0.82 | CES2 (0.66) | CES2CES1LMNAMAPK1POLB | |
| SCHEMBL31407025 | 0.82 | CES2 (0.66) | CES2CES1LMNAMAPK1POLB | |
| SCHEMBL23972274 | 0.82 | CES2 (0.66) | CES2CES1LMNAMAPK1POLB | |
| SCHEMBL7963208 | 0.82 | CES2 (0.44) | CES2CES1LMNAMAPK1POLB | |
| SCHEMBL31407017 | 0.82 | CES2 (0.66) | CES2CES1LMNAMAPK1POLB | |
| SCHEMBL8013319 | 0.81 | CES2 (0.52) | CES2CES1ALDH1A1 | |
| SCHEMBL23972666 | 0.79 | PPARG (0.46) | CES2CES1KMT2A | |
| SCHEMBL195340 | 0.78 | CES2 (0.49) | CES2CES1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008078350-A2 | PROCESS FOR THE PREPARATION OF FLUOROPHENYLACETIC ACIDS AND DERIVATIVES THEREOF | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2008-07-03 | — | — | WO | disclosed |