Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.89 |
| ▸ | THRB | P10828 | 1/20 | 0.89 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decane SCHEMBL23174724 | 1.00 | TSHR (0.89) | TSHRTHRBLMNAHTTDNM1 | |
| Nonane SCHEMBL27486798 | 1.00 | TSHR (0.89) | TSHRTHRBLMNAHTTDNM1 | |
| Octane SCHEMBL8988185 | 1.00 | — | — | |
| SCHEMBL23174725 | 1.00 | TSHR (0.89) | TSHRTHRBLMNAHTTDNM1 | |
| Heptane SCHEMBL8568059 | 1.00 | — | — | |
| Heptane SCHEMBL28095754 | 0.95 | — | — | |
| Heptane SCHEMBL23091221 | 0.95 | TSHR (0.80) | TSHRTHRBLMNAHTTDNM1 | |
| Heptane SCHEMBL17968620 | 0.95 | TSHR (0.80) | TSHRTHRBLMNAHTTDNM1 | |
| Tetradecane SCHEMBL23924271 | 0.94 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Hexadecane SCHEMBL23499901 | 0.94 | TSHR (1.00) | TSHRTHRBLMNADNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220694-B | A kind of preparation method of neohesperidin dihydrochalcone | 湖南华诚生物资源股份有限公司 | 2019-03-26 | — | — | CN | claimed |
| CN-106220694-A | A kind of preparation method of NHDC | 湖南华诚生物资源股份有限公司 | 2016-12-14 | — | — | CN | claimed |
| CN-106220694-B | A kind of preparation method of neohesperidin dihydrochalcone | 湖南华诚生物资源股份有限公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-106220694-A | A kind of preparation method of NHDC | 湖南华诚生物资源股份有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-100516017-C | Process for the carbonylation of an ethylenically unsaturated compound and catalyst therefore | Shell int research co ltd (NL) | 2009-07-22 | — | — | CN | disclosed |
| US-20080086015-A1 | Alkoxycarbonylation of Vinyl Esters | LUCITE INTERNATIONAL UK LTD. (GB) | 2008-04-10 | — | — | US | disclosed |
| EP-1748976-A1 | ALKOXYCARBONYLATION OF VINYL ESTERS | Lucite International UK Limited (GB) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005118519-A1 | ALKOXYCARBONYLATION OF VYNIL ESTERS | LUCITE INTERNATIONAL UK LTD (GB) | 2005-12-15 | — | — | WO | disclosed |
| CN-1642646-A | Process for the carbonylation of an ethylenically unsaturated compound and catalyst therefore | SHELL INT RESEARCH (NL) | 2005-07-20 | — | — | CN | disclosed |
| EP-1478463-A1 | PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND CATALYST THEREFORE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003070370-A1 | PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND CATALYST THEREFORE | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080086015-A1 | Alkoxycarbonylation of Vinyl Esters | HAO2, HAO1, LDHA | TSHR 3239/4885THRB 892/4885LMNA 1841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.