SCHEMBL5085193

SCHEMBL5085193

CCCCc1ccc2c(c1C1=CC=CC1)[CH]c1cccc(C)c1-2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.31
CTSG P08311 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5086259 0.85 ELANE (0.33) ELANECTSG
SCHEMBL7197068 0.76 NR1H2 (0.35) ELANECTSG
SCHEMBL5085995 0.75
SCHEMBL27608664 0.68 CYP2A6 (0.35)
SCHEMBL7153257 0.67
SCHEMBL8975306 0.66 TAAR1 (0.43)
SCHEMBL7719570 0.65 MYC (0.34)
SCHEMBL15610000 0.64
SCHEMBL2867536 0.64 ALOX5 (0.33) ELANECTSG
SCHEMBL1029658 0.63 NR1H2 (0.38) ELANECTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1283223-A2 Polyolefin production ATOFINA Research (BE) 2003-02-12 EP claimed
EP-0881236-A1 Metallocene catalyst component for use in producing isotactic polyolefins FINA RESEARCH S.A. (BE) 1998-12-02 EP claimed
EP-1283223-B1 Use of a mixture of two metallocene regioisomers as catalyst component for preparing bimodal isotactic polyolefins TOTAL PETROCHEMICALS RES FELUY (BE) 2008-04-09 EP disclosed
EP-1163278-B1 USE AND PRODUCTION OF POLYPROPYLENE TOTAL PETROCHEMICALS RES FELUY (BE) 2007-01-10 EP disclosed
US-20040249094-A1 Use and production of polypropylene ATOFINA RESEARCH, S.A. (BE) 2004-12-09 US disclosed
US-6727332-B2 SPECIFIC METALLOCENE CATALYSTS USED TO PREPARE PROPYLENE POLYMERS WITH LOW MELTING TEMPERATURE, HIGH CRYSTALLISATION TEMPERATURE AND HIGH TRANSPARENCY; HIGH SPEED SOLIDIFICATION FROM MELT ATOFINA RESEARCH S.A. (BE) 2004-04-27 US disclosed
EP-0984989-B1 USE OF METALLOCENE CATALYSTS FOR PRODUCING REGIOSPECIFIC, ISOTACTIC POLYOLEFINS ATOFINA RES (BE) 2003-06-25 EP disclosed
EP-1283223-A2 Polyolefin production ATOFINA Research (BE) 2003-02-12 EP disclosed
US-20020120080-A1 Use and production of polypropylene ATOFINA RESEARCH, S.A. (BE) 2002-08-29 US disclosed
EP-1163278-A1 USE AND PRODUCTION OF POLYPROPYLENE ATOFINA Research (BE) 2001-12-19 EP disclosed
WO-2000050476-A1 USE AND PRODUCTION OF POLYPROPYLENE ATOFINA RESEARCH (BE) 2000-08-31 WO disclosed
EP-1031582-A1 Use and production of polypropylene FINA RESEARCH S.A. (BE) 2000-08-30 EP disclosed
EP-0984989-A1 METALLOCENE CATALYST COMPONENT FOR USE IN PRODUCING ISOTACTIC POLYOLEFINS FINA RESEARCH S.A. (BE) 2000-03-15 EP disclosed
WO-1998054230-A1 METALLOCENE CATALYST COMPONENT FOR USE IN PRODUCING ISOTACTIC POLYOLEFINS FINA RESEARCH S.A. (BE) 1998-12-03 WO disclosed
EP-0881236-A1 Metallocene catalyst component for use in producing isotactic polyolefins FINA RESEARCH S.A. (BE) 1998-12-02 EP disclosed