SCHEMBL5085202

SCHEMBL5085202

COC=CCCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 13/20 0.47
EGFR P00533 1/20 0.42
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1814080 0.83 GPR52 (0.48) GPR52MAOB
SCHEMBL23188649 0.82 CYP1A2 (0.43) GPR52
SCHEMBL755405 0.80 TAAR1 (0.42) MAOB
SCHEMBL755404 0.80 TAAR1 (0.42) MAOB
SCHEMBL9457643 0.80 GPR52 (0.33) GPR52
SCHEMBL9457648 0.80 GPR52 (0.33) GPR52
SCHEMBL7762166 0.79 GPR52 (0.57) GPR52MAOB
SCHEMBL9715286 0.79 GPR52 (0.57) GPR52MAOB
SCHEMBL7762164 0.79 GPR52 (0.57) GPR52MAOB
SCHEMBL1157684 0.78 GPR52 (0.42) GPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3189021-B1 METATHESIS POLYMERIZATION METHODS UNIV WASHINGTON (US) 2025-05-14 EP disclosed
WO-2024204738-A1 METHOD FOR PRODUCING 1,1-DIMETHYL-1,2-DIHYDRONAPHTHALENE 持田製薬株式会社 2024-10-03 WO disclosed
US-11932714-B2 Copolymer, film composition and composite material employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2024-03-19 US disclosed
US-20230063240-A1 COPOLYMER, FILM COMPOSITION AND COMPOSITE MATERIAL EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-03-02 US disclosed
CN-115677932-A Copolymer, film composition comprising the same, and composite material 财团法人工业技术研究院 2023-02-03 CN disclosed
CN-108250720-B Oligomer, composition containing same and composite material 财团法人工业技术研究院 2021-03-23 CN disclosed
US-10907010-B2 Metathesis polymerization methods UNIVERSITY OF WASHINGTON (US) 2021-02-02 US disclosed
US-20190211143-A1 METATHESIS POLYMERIZATION METHODS UNIVERSITY OF WASHINGTON (US) 2019-07-11 US disclosed
US-10273327-B2 Metathesis polymerization methods UNIVERSITY OF WASHINGTON (US) 2019-04-30 US disclosed
US-20170240695-A1 METATHESIS POLYMERIZATION METHODS UNIVERSITY OF WASHINGTON (US) 2017-08-24 US disclosed
US-20170240695-A1 METATHESIS POLYMERIZATION METHODS UNIVERSITY OF WASHINGTON (US) 2017-08-24 US disclosed
WO-2016036976-A1 METATHESIS POLYMERIZATION METHODS UNIVERSITY OF WASHINGTON (US) 2016-03-10 WO disclosed
EP-1658298-B1 PHOSPHORUS-CONTAINING IMIDAZOLINES AND METAL COMPLEXES THEREOF SOLVIAS AG (CH) 2008-03-26 EP disclosed
US-20070010493-A1 Phospinite-imidazolines and metal complexes thereof SOLVIAS AG (CH) 2007-01-11 US disclosed
EP-1658298-A2 NOVEL ORGANIC COMPOUNDS AND METAL COMPLEXES Solvias AG (CH) 2006-05-24 EP disclosed
WO-2005021562-A2 PHOSPINITE-IMIDAZOLINES AND METAL COMPLEXES THEREOF SOLVIAS AG (CH) 2005-03-10 WO disclosed
EP-1478403-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA, INC. (CA) 2004-11-24 EP disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010493-A1 Phospinite-imidazolines and metal complexes thereof H1-0, H1-2, H1-3 GPR52 48/4885EGFR 1559/4885MAOB 2781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.