Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TAF1 | P21675 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CECR2 | Q9BXF3 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5141508 | 0.79 | CNR2 (0.59) | HPGDKMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL5081771 | 0.79 | SMN1; SMN2 (0.41) | HPGDKMT2AEPAS1SMN1; SMN2PHGDH | |
| SCHEMBL3990689 | 0.73 | LMNA (0.50) | TAF1SMN1; SMN2PHGDHTSHRBRD9 | |
| SCHEMBL5359457 | 0.68 | CNR2 (0.44) | TAF1PKMJAK1 | |
| SCHEMBL25280173 | 0.68 | HPGD (0.52) | HPGDKMT2AEPAS1SMN1; SMN2PKM | |
| SCHEMBL4205586 | 0.67 | PHGDH (0.50) | HPGDKMT2AEPAS1SMN1; SMN2PKM | |
| SCHEMBL19657107 | 0.66 | KDM4E (0.51) | HPGDKMT2ASMN1; SMN2PHGDHTSHR | |
| SCHEMBL29853928 | 0.66 | PTPRC (0.42) | KMT2ASMN1; SMN2JAK1ALDH1A1MAPK1 | |
| SCHEMBL29045251 | 0.66 | PTPRC (0.42) | KMT2ASMN1; SMN2JAK1ALDH1A1MAPK1 | |
| SCHEMBL7854134 | 0.65 | KMT2A (0.60) | HPGDKMT2AEPAS1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116816-A1 | COMBINATION OF CB2 LIGAND AND PARACETAMOL | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |