Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085235 | 0.79 | HPGD (0.45) | SMN1; SMN2KMT2AEPAS1HTTHPGD | |
| SCHEMBL5087486 | 0.71 | KDM4E (0.43) | SMN1; SMN2HTTHPGDALDH1A1 | |
| SCHEMBL4448054 | 0.70 | LRRK2 (0.44) | SMN1; SMN2KMT2AHTTBTKPHGDH | |
| SCHEMBL2957069 | 0.69 | MAPT (0.41) | SMN1; SMN2KMT2AHTTPHGDHTSHR | |
| SCHEMBL25280173 | 0.68 | HPGD (0.52) | SMN1; SMN2KMT2AEPAS1HTTHPGD | |
| SCHEMBL19657112 | 0.67 | HTT (0.47) | SMN1; SMN2HTTHPGDBTKTSHR | |
| SCHEMBL19657110 | 0.67 | ACACB (0.53) | SMN1; SMN2HPGDBTKALDH1A1 | |
| SCHEMBL11300565 | 0.66 | ALDH1A1 (0.40) | SMN1; SMN2KMT2ABTKALDH1A1MAPK1 | |
| SCHEMBL31733057 | 0.65 | POLB (0.41) | KMT2ABTKLRRK2JAK2 | |
| SCHEMBL11325494 | 0.65 | POLB (0.41) | KMT2ABTKLRRK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116816-A1 | COMBINATION OF CB2 LIGAND AND PARACETAMOL | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |