SCHEMBL5085327

SCHEMBL5085327

COC(=O)Nc1cc(NC(=O)OC)c(NC(=O)OC)cc1NC(=O)OC

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.68
ALOX15 P16050 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
HTT P42858 2/20 0.46
PKM P14618 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
MAPT P10636 2/20 0.44
PLAU P00749 1/20 0.42
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 2/20 0.42
LMNA P02545 1/20 0.42
FAAH O00519 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5084623 0.91 HPGD (0.59) HPGDALOX15SMN1; SMN2HTTPKM
SCHEMBL5084656 0.91 HPGD (0.59) HPGDALOX15SMN1; SMN2HTTPKM
SCHEMBL11658876 0.87 HPGD (0.67) HPGDALOX15SMN1; SMN2HTTPKM
SCHEMBL10099723 0.84 HPGD (0.52) HPGDALOX15SMN1; SMN2HTTPKM
SCHEMBL11657425 0.82 HPGD (0.55) HPGDALOX15SMN1; SMN2HTTPKM
SCHEMBL11661335 0.82 HPGD (0.60) HPGDALOX15SMN1; SMN2HTTMEN1
SCHEMBL5085272 0.80 HPGD (0.53) HPGDALOX15SMN1; SMN2HTTMEN1
SCHEMBL5085409 0.80 HPGD (0.53) HPGDALOX15SMN1; SMN2HTTMEN1
SCHEMBL11657782 0.80 HPGD (0.69) HPGDSMN1; SMN2HTTPKMMEN1
SCHEMBL11659356 0.79 HPGD (0.64) HPGDALOX15SMN1; SMN2HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 EP disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed