SCHEMBL5085382

SCHEMBL5085382

O=C(O)Oc1cc(OC(=O)O)c(OC(=O)O)c(OC(=O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
BACE1 P56817 2/20 0.36
TOP1 P11387 3/20 0.34
MAPT P10636 3/20 0.33
ALOX5 P09917 2/20 0.33
MAPK1 P28482 2/20 0.33
ELANE P08246 2/20 0.32
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32
TUBB6 Q9BUF5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1552645 0.86 KDM4E (0.33) KDM4EBACE1
SCHEMBL8030911 0.81 KDM4E (0.37) KDM4EBACE1MAPTALOX5MAPK1
SCHEMBL7190643 0.81 PKM (0.39) KDM4EBACE1MAPTMAPK1ELANE
SCHEMBL10872006 0.80 TNFSF11 (0.30) KDM4EMAPTALDH1A1GAAKMT2A
SCHEMBL1551913 0.79 KDM4E (0.36) KDM4EBACE1MAPTMAPK1ELANE
SCHEMBL6575964 0.79 KDM4E (0.40) KDM4EBACE1MAPTALOX5MAPK1
SCHEMBL322525 0.79 LMNA (0.40) KDM4EBACE1MAPTELANEALDH1A1
SCHEMBL9670322 0.76 USP2 (0.47) KDM4EMAPK1TUBB4ATUBBTUBA3C
SCHEMBL5678543 0.76 KDM4E (0.46) KDM4EMAPTMAPK1ELANEALDH1A1
SCHEMBL686585 0.74 KDM4E (0.48) KDM4EMAPTMAPK1ELANEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785241-A2 Effect powder paint, its preparation and application HÜLS AKTIENGESELLSCHAFT (DE) 1997-07-23 EP claimed
EP-1983024-A1 Material mixture based on alkylbenzyl esters Lanxess Deutschland GmbH (DE) 2008-10-22 EP disclosed
EP-0881262-B1 Curable composition on the basis of polymers containing free carboxylic groups VANTICO AG (CH) 2003-11-19 EP disclosed
EP-0859585-B1 HAIR TREATMENT COMPOSITION BASF AG (DE) 2002-09-11 EP disclosed
EP-0697440-B1 Heat-hardenable composition, especially suited for use as automotive paints VANTICO AG (CH) 2001-11-14 EP disclosed
EP-0881262-A2 Curable composition on the basis of polymers containing free carboxylic groups Ciba SC Holding AG (CH) 1998-12-02 EP disclosed
EP-0536085-B1 Solid compositions based on polyglycidyl compounds having a molecular weight lower than 1500 CIBA GEIGY AG (CH) 1998-11-11 EP disclosed
EP-0859585-A1 HAIR TREATMENT COMPOSITION BASF AKTIENGESELLSCHAFT (DE) 1998-08-26 EP disclosed
EP-0785241-A2 Effect powder paint, its preparation and application HÜLS AKTIENGESELLSCHAFT (DE) 1997-07-23 EP disclosed
WO-1997017052-A1 HAIR TREATMENT COMPOSITION BASF AKTIENGESELLSCHAFT (DE) 1997-05-15 WO disclosed
EP-0085913-A1 Reactive polymers containing carboxylic groups, process for their production and their use as curing agents in powder lacquers BAYER AG (DE) 1983-08-17 EP disclosed
EP-0012379-B1 LAQUER MIXTURE AND COATING MATERIAL CONTAINING POLYAMIDE HYDANTOINS BAYER AG (DE) 1983-06-01 EP disclosed
EP-0015479-B1 THERMALLY STABLE CROSSLINKED POLYMERS, THEIR APPLICATION, AND SOLUTIONS OR MIXTURES CONTAINING THEM, WITH THEIR APPLICATION BAYER AG (DE) 1983-04-13 EP disclosed
EP-0012381-B1 PROCESS FOR THE PREPARATION OF COMPOUNDS CONTAINING HYDANTOIN GROUPS BAYER AG (DE) 1982-12-15 EP disclosed
EP-0024680-B1 POWDER PAINT BINDERS AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1982-06-09 EP disclosed
EP-0051787-A2 Amidines and amidine/isocyanate adducts, methods of preparing them and their use as catalysts in curing epoxy resins BAYER AG (DE) 1982-05-19 EP disclosed
EP-0024680-A1 Powder paint binders and process for their preparation BAYER AG (DE) 1981-03-11 EP disclosed
EP-0018949-A1 Curable epoxy resin mixtures and curing accelerators therefore CIBA-GEIGY AG (CH) 1980-11-12 EP disclosed
EP-0015479-A1 Thermally stable crosslinked polymers, their application, and solutions or mixtures containing them, with their application BAYER AG (DE) 1980-09-17 EP disclosed
EP-0012381-A1 Process for the preparation of compounds containing hydantoin groups BAYER AG (DE) 1980-06-25 EP disclosed