Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.41 |
| ▸ | HTR1A | P08908 | 11/20 | 0.41 |
| ▸ | HTR2B | P41595 | 11/20 | 0.41 |
| ▸ | HTR5A | P47898 | 10/20 | 0.41 |
| ▸ | HTR1D | P28221 | 9/20 | 0.41 |
| ▸ | HTR1B | P28222 | 9/20 | 0.41 |
| ▸ | HTR2A | P28223 | 9/20 | 0.41 |
| ▸ | HTR6 | P50406 | 7/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | HTR1E | P28566 | 6/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432201 | 0.79 | CETP (0.41) | APPALDH1A1KDM4EHPGD | |
| SCHEMBL5085400 | 0.76 | HTR7 (0.47) | HTR7HTR1AHTR2BHTR5AHTR1D | |
| SCHEMBL15637636 | 0.76 | APP (0.44) | HTR7APPALDH1A1KDM4EHPGD | |
| SCHEMBL27695180 | 0.75 | TRPV4 (0.36) | HSP90AA1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29788337 | 0.72 | CA1 (0.71) | HTR7APPALDH1A1KDM4EHPGD | |
| SCHEMBL301996 | 0.72 | CA1 (0.71) | HTR7APPALDH1A1KDM4EHPGD | |
| SCHEMBL29429633 | 0.72 | CA1 (0.71) | HTR7APPALDH1A1KDM4EHPGD | |
| SCHEMBL3664870 | 0.71 | APP (0.40) | HTR7HSP90AA1APPALDH1A1KDM4E | |
| SCHEMBL3664873 | 0.71 | APP (0.40) | HTR7HSP90AA1APPALDH1A1KDM4E | |
| SCHEMBL3643541 | 0.70 | CA1 (0.67) | HTR7APPALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |