SCHEMBL5085428

SCHEMBL5085428

CCCC[Si](C)(C)OCC(CO[Si](C)(C)CCCC)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
KCNH2 Q12809 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
LMNA P02545 1/20 0.33
CYP2D6 P10635 1/20 0.33
CTSK P43235 1/20 0.32
EPHX2 P34913 1/20 0.32
DNM1 Q05193 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085457 0.94 SLC6A2 (0.31) SLC6A2TAAR1KCNH2CTSK
SCHEMBL5080955 0.93 ALDH1A1 (0.32) SLC6A2TAAR1KCNH2SMN1; SMN2
SCHEMBL5077395 0.92 ALDH1A1 (0.32)
SCHEMBL5081803 0.90 SLC6A2 (0.36) SLC6A2TAAR1SMN1; SMN2LMNACYP2D6
SCHEMBL5078138 0.85 SLC6A2 (0.33) SLC6A2TAAR1LMNACYP2D6
SCHEMBL5081735 0.84 TAAR1 (0.36) SLC6A2TAAR1KCNH2SMN1; SMN2LMNA
SCHEMBL5080806 0.84 ALDH1A1 (0.33) SLC6A2TAAR1SMN1; SMN2LMNACYP2D6
SCHEMBL5085326 0.83 SLC6A2 (0.38) SLC6A2TAAR1SMN1; SMN2LMNACYP2D6
SCHEMBL5075143 0.82 SLC6A2 (0.31) SLC6A2TAAR1
SCHEMBL5075136 0.80 SMN1; SMN2 (0.33) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed