Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ACP3 | P15309 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087907 | 1.00 | ALDH1A1 (0.51) | ALDH1A1ACP3SIGMAR1CYP1A2THRB | |
| SCHEMBL27853244 | 1.00 | ALDH1A1 (0.51) | ALDH1A1ACP3SIGMAR1CYP1A2THRB | |
| SCHEMBL8065362 | 0.88 | ALDH1A1 (0.62) | ALDH1A1SIGMAR1GAATRPM8MEN1 | |
| SCHEMBL29060375 | 0.88 | ALDH1A1 (0.62) | ALDH1A1SIGMAR1GAATRPM8MEN1 | |
| SCHEMBL8349459 | 0.88 | ALDH1A1 (0.62) | ALDH1A1SIGMAR1GAATRPM8MEN1 | |
| SCHEMBL8093317 | 0.88 | ALDH1A1 (0.54) | ALDH1A1ACP3SIGMAR1TRPM8MEN1 | |
| Hydrochloric Acid SCHEMBL28019583 | 0.87 | ALDH1A1 (0.60) | ALDH1A1ACP3SIGMAR1GAAMEN1 | |
| SCHEMBL7876545 | 0.87 | ALDH1A1 (0.53) | ALDH1A1SIGMAR1TRPM8MEN1KMT2A | |
| SCHEMBL7599136 | 0.87 | ALDH1A1 (0.53) | ALDH1A1SIGMAR1TRPM8MEN1KMT2A | |
| SCHEMBL31336702 | 0.87 | ALDH1A1 (0.53) | ALDH1A1SIGMAR1TRPM8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426727-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | Hangzhou Dac Biotech Co., Ltd. (CN) | 2024-09-11 | — | — | EP | disclosed |
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2023-04-13 | — | — | US | disclosed |
| US-20230010108-A1 | A CONJUGATION LINKER CONTAINING 2,3-DIAMINOSUCCINYL GROUP | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-01-12 | — | — | US | disclosed |
| WO-2022078524-A4 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |
| EP-3986463-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2022-04-27 | — | — | EP | disclosed |
| WO-2022078524-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
| CN-114040779-A | Conjugates of cell binding molecules containing branched linkers and cytotoxic agents | 杭州多禧生物科技有限公司 | 2022-02-11 | — | — | CN | disclosed |
| US-20210169896-A1 | A CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-06-10 | — | — | US | disclosed |
| CN-105061238-A | Preparation method of 2,3-bis(benzylamino)butanedioic acid | ANHUI LANGXI LIANKE IND CO LTD | 2015-11-18 | — | — | CN | disclosed |
| CN-105061238-A | Preparation method of 2,3-bis(benzylamino)butanedioic acid | ANHUI LANGXI LIANKE IND CO LTD | 2015-11-18 | — | — | CN | disclosed |
| WO-2008071696-A1 | IMPROVED PROCESS FOR PREPARING SUBSTITUTED CARBOXYLIC ANHYDRIDES | DSM IP ASSETS BV (CH) | 2008-06-19 | — | — | WO | disclosed |
| JP-2006241091-A | METHOD FOR PRODUCING 1,3-DIBENZYL-2-OXOIMIDAZOLIDINE-4,5-DICARBOXYLIC ACID | SUMITOMO CHEMICAL CO LTD | 2006-09-14 | — | — | JP | disclosed |
| JP-2006232742-A | METHOD FOR PRODUCING 2, 3-BIS-(BENZYLAMINO)SUCCINIC ACID | SUMITOMO CHEMICAL CO LTD | 2006-09-07 | — | — | JP | disclosed |
| JP-2006193480-A | METHOD FOR PRODUCING 1,3-DIBENZYL-2-OXOIMIDAZOLIDINE-4,5-DICARBOXYLIC ACID | SUMITOMO CHEMICAL CO LTD | 2006-07-27 | — | — | JP | disclosed |
| CN-1152018-C | Process for preparing 1,3-dibenzyl imidazoline-2-ketone-cis-4, 5-dicarboxylic acid (I) | 复旦大学 | 2004-06-02 | — | — | CN | disclosed |
| CN-1434039-A | Process for preparing 1,3-dibenzyl imidazoline-2-ketone-cis-4, 5-dicarboxylic acid (I) | UNIV FUDAN (CN) | 2003-08-06 | — | — | CN | disclosed |
| US-5610141-A | CELL DIVISION STIMULANT | NYCOMED IMAGING AS (NO) | 1997-03-11 | — | — | US | disclosed |
| EP-0673388-A1 | DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY | NYCOMED IMAGING AS (NO) | 1995-09-27 | — | — | EP | disclosed |
| WO-1993024523-A1 | DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY | HAFSLUND NYCOMED AS (NO) | 1993-12-09 | — | — | WO | disclosed |
| US-5151525-A | Process for producing 2-oxo-1,3-dibenzyl-4,5-cis-imidazolidinedicarboxylic acid | PPG INDUSTRIES, INC. (US) | 1992-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210169896-A1 | A CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES | PBDC1, BRD2, CD79B | ALDH1A1 2260/4885ACP3 2764/4885SIGMAR1 4104/4885 |
| US-20230010108-A1 | A CONJUGATION LINKER CONTAINING 2,3-DIAMINOSUCCINYL GROUP | DAO, DDO, DCLRE1A | ALDH1A1 60/4885ACP3 1508/4885SIGMAR1 1688/4885 |
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | CD2BP2, EPCAM, CD74 | ALDH1A1 2397/4885ACP3 1592/4885SIGMAR1 3560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.