Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.80 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185751 | 0.84 | ABCG2 (0.88) | ABCG2MAOACYP1A2CYP2D6CYP1A1 | |
| SCHEMBL7185747 | 0.84 | ABCG2 (0.88) | ABCG2MAOACYP1A2CYP2D6CYP1A1 | |
| SCHEMBL979720 | 0.83 | ABCG2 (0.87) | ABCG2MAOACYP1A2CYP2D6CYP1A1 | |
| SCHEMBL979719 | 0.83 | ABCG2 (0.87) | ABCG2MAOACYP1A2CYP2D6CYP1A1 | |
| SCHEMBL9338183 | 0.83 | ABCG2 (0.54) | ABCG2MAOACYP1A2CYP2D6CYP1A1 | |
| SCHEMBL7192430 | 0.82 | ABCG2 (0.85) | ABCG2MAOACYP1A2CYP2D6CYP1A1 | |
| SCHEMBL7101379 | 0.82 | ABCG2 (0.85) | ABCG2MAOACYP1A2CYP2D6CYP1A1 | |
| SCHEMBL9338192 | 0.82 | ABCG2 (0.74) | ABCG2MAOACYP1A2CYP2D6CYP1A1 | |
| SCHEMBL9338182 | 0.82 | ABCG2 (0.74) | ABCG2MAOACYP1A2CYP2D6CYP1A1 | |
| SCHEMBL7198506 | 0.81 | ABCG2 (0.72) | ABCG2MAOAMAOBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018692-A1 | NOVEL CHALCONE DERIVATIVES WHICH INHIBIT THE IL-5 ACTIVITY | THE INDUSTRY AND ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) (KR) | 2008-02-14 | — | — | WO | disclosed |