Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.88 |
| ▸ | MAOB | P27338 | 1/20 | 0.71 |
| ▸ | CTSL | P07711 | 4/20 | 0.63 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.63 |
| ▸ | CTSB | P07858 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.57 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185751 | 1.00 | ABCG2 (0.88) | ABCG2MAOBCTSLCAPN1CTSB | |
| SCHEMBL979719 | 0.87 | ABCG2 (0.87) | ABCG2MAOBMAOAMAPTRAB9A | |
| SCHEMBL979720 | 0.87 | ABCG2 (0.87) | ABCG2MAOBMAOAMAPTRAB9A | |
| SCHEMBL7192430 | 0.86 | ABCG2 (0.85) | ABCG2MAOBCTSLCTSBMAOA | |
| SCHEMBL7101379 | 0.86 | ABCG2 (0.85) | ABCG2MAOBCTSLCTSBMAOA | |
| SCHEMBL7185827 | 0.85 | ABCG2 (0.63) | ABCG2MAOBCTSLCAPN1CTSB | |
| SCHEMBL7185831 | 0.85 | ABCG2 (0.63) | ABCG2MAOBCTSLCAPN1CTSB | |
| SCHEMBL7184176 | 0.84 | ABCG2 (0.61) | ABCG2MAOBCTSLCAPN1CTSB | |
| SCHEMBL7186899 | 0.84 | ABCG2 (0.61) | ABCG2MAOBCTSLCAPN1CTSB | |
| SCHEMBL7184186 | 0.84 | ABCG2 (0.61) | ABCG2MAOBCTSLCAPN1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |