Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5089830 | 0.96 | GAA (0.45) | GAATHRBSMN1; SMN2GPR119JAK2 | |
| SCHEMBL16392288 | 0.85 | GPR119 (0.46) | GAATHRBSMN1; SMN2GPR119JAK2 | |
| SCHEMBL15312958 | 0.84 | GAA (0.48) | GAATHRBSMN1; SMN2GPR119JAK2 | |
| SCHEMBL5083592 | 0.83 | SMN1; SMN2 (0.50) | GAATHRBSMN1; SMN2GPR119JAK2 | |
| SCHEMBL1773896 | 0.81 | GPR119 (0.56) | GAATHRBSMN1; SMN2GPR119JAK2 | |
| SCHEMBL2400320 | 0.81 | USP30 (0.47) | GAATHRBSMN1; SMN2GPR119JAK2 | |
| SCHEMBL2581282 | 0.80 | GPR119 (0.44) | GAATHRBSMN1; SMN2GPR119JAK2 | |
| SCHEMBL20541282 | 0.79 | GPR119 (0.49) | GAATHRBSMN1; SMN2GPR119ACKR3 | |
| SCHEMBL15312890 | 0.79 | GPR119 (0.47) | THRBGPR119MAPT | |
| SCHEMBL419123 | 0.79 | GPR119 (0.51) | THRBSMN1; SMN2GPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |