Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085617 | 0.83 | GAA (0.45) | SMN1; SMN2GAATHRBGPR119JAK2 | |
| SCHEMBL2578274 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2GAATHRBGPR119JAK2 | |
| SCHEMBL5089830 | 0.79 | GAA (0.45) | SMN1; SMN2GAATHRBGPR119JAK2 | |
| SCHEMBL2581432 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2GAATHRBGPR119MAPT | |
| SCHEMBL18689610 | 0.75 | GPR119 (0.46) | SMN1; SMN2GAATHRBGPR119MAPT | |
| SCHEMBL2579967 | 0.75 | NAMPT (0.42) | SMN1; SMN2GAATHRBGPR119MAPT | |
| SCHEMBL2579312 | 0.74 | GPR119 (0.46) | SMN1; SMN2GAATHRBGPR119MAPT | |
| SCHEMBL1118173 | 0.74 | ALDH1A1 (0.49) | SMN1; SMN2GAATHRBGPR119MAPT | |
| SCHEMBL3358948 | 0.73 | KDM4E (0.59) | SMN1; SMN2GAATHRBGPR119JAK2 | |
| SCHEMBL13913655 | 0.71 | KDM4E (0.60) | SMN1; SMN2GAATHRBGPR119JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |