Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085871 | 1.00 | TDP1 (0.46) | TDP1TAS1R3TAS1R1EGFRHDAC3 | |
| SCHEMBL5083397 | 0.93 | ALDH1A1 (0.45) | TDP1TAS1R3TAS1R1EGFRALDH1A1 | |
| SCHEMBL5083402 | 0.93 | ALDH1A1 (0.45) | TDP1TAS1R3TAS1R1EGFRALDH1A1 | |
| SCHEMBL5083350 | 0.91 | ALDH1A1 (0.44) | TDP1EGFRHDAC3ALDH1A1LMNA | |
| SCHEMBL5083353 | 0.91 | ALDH1A1 (0.44) | TDP1EGFRHDAC3ALDH1A1LMNA | |
| SCHEMBL5082182 | 0.91 | AKR1B10 (0.46) | TDP1TAS1R3TAS1R1EGFRHDAC3 | |
| SCHEMBL5082178 | 0.91 | AKR1B10 (0.46) | TDP1TAS1R3TAS1R1EGFRHDAC3 | |
| SCHEMBL5941235 | 0.89 | KMT2A (0.45) | TDP1EGFRHDAC3ALDH1A1LMNA | |
| SCHEMBL5941231 | 0.89 | KMT2A (0.45) | TDP1EGFRHDAC3ALDH1A1LMNA | |
| SCHEMBL5079953 | 0.88 | TDP1 (0.44) | TDP1EGFRHDAC3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746110-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF | CHINA PETROLEUM & CHEMICAL (CN) | 2015-03-11 | — | — | EP | disclosed |
| US-7351778-B2 | Catalyst component for olefin polymerization and catalyst comprising the same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-04-01 | — | — | US | disclosed |
| EP-1746110-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF | China Petroleum & Chemical Corporation (CN) | 2007-01-24 | — | — | EP | disclosed |
| US-20060287446-A1 | Catalyst component for olefin polymerization and catalyst comprising the same | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) | 2006-12-21 | — | — | US | disclosed |