Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.85 |
| ▸ | RBM39 | Q14498 | 1/20 | 0.85 |
| ▸ | GFER | P55789 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508604 | 1.00 | MAPT (0.85) | MAPTALDH1A1RBM39GFERKMT2A | |
| SCHEMBL13908103 | 0.92 | MAPT (0.77) | MAPTALDH1A1RBM39GFERKMT2A | |
| SCHEMBL30480917 | 0.92 | MAPT (0.77) | MAPTALDH1A1RBM39GFERKMT2A | |
| SCHEMBL10027946 | 0.92 | MAPT (0.77) | MAPTALDH1A1RBM39GFERKMT2A | |
| SCHEMBL13908088 | 0.80 | ALDH1A1 (0.81) | MAPTALDH1A1RBM39KMT2AMEN1 | |
| SCHEMBL13908089 | 0.80 | KMT2A (0.75) | MAPTALDH1A1RBM39KMT2AMEN1 | |
| SCHEMBL10027945 | 0.78 | ALDH1A1 (0.77) | MAPTALDH1A1RBM39KMT2AMEN1 | |
| SCHEMBL14905767 | 0.77 | ALDH1A1 (0.75) | MAPTALDH1A1RBM39KMT2AMEN1 | |
| SCHEMBL13908086 | 0.76 | ALDH1A1 (0.73) | MAPTALDH1A1RBM39KMT2AMEN1 | |
| SCHEMBL13908239 | 0.76 | ALDH1A1 (0.73) | MAPTALDH1A1RBM39KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130143935-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130143935-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130143935-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-06-06 | — | — | US | disclosed |
| US-8318951-B2 | Stem cell differentiating agents and uses therefor | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-11-27 | — | — | US | disclosed |
| US-20120029200-A1 | Stem Cell Differentiating Agents and Uses Therefor | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-02 | — | — | US | disclosed |
| US-20120029200-A1 | Stem Cell Differentiating Agents and Uses Therefor | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-02 | — | — | US | disclosed |
| US-20120029200-A1 | Stem Cell Differentiating Agents and Uses Therefor | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-02 | — | — | US | disclosed |
| US-7981935-B2 | Stem cell differentiating agents and uses therefor | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-07-19 | — | — | US | disclosed |
| US-7981935-B2 | Stem cell differentiating agents and uses therefor | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-07-19 | — | — | US | disclosed |
| US-7981935-B2 | Stem cell differentiating agents and uses therefor | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-07-19 | — | — | US | disclosed |
| WO-2009038879-A2 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-03-26 | — | — | WO | disclosed |
| US-20090076103-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-03-19 | — | — | US | disclosed |
| US-20090076103-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-03-19 | — | — | US | disclosed |
| US-20090076103-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029200-A1 | Stem Cell Differentiating Agents and Uses Therefor | MYADM, MCL1, NOTCH4 | MAPT 4235/4885ALDH1A1 28/4885RBM39 3747/4885 |
| US-20090076103-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | MYADM, MCL1, NOTCH4 | MAPT 4235/4885ALDH1A1 28/4885RBM39 3747/4885 |
| US-20130143935-A1 | STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR | MYADM, MCL1, NOTCH4 | MAPT 4235/4885ALDH1A1 28/4885RBM39 3747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.