Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 6/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163020 | 1.00 | ALDH1A1 (0.55) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL4729976 | 0.94 | KCNH2 (0.51) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7162212 | 0.94 | KCNH2 (0.51) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7160178 | 0.91 | ALDH1A1 (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL5086246 | 0.91 | ALDH1A1 (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7165477 | 0.87 | ALDH1A1 (0.51) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7160246 | 0.85 | KCNH2 (0.53) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL4729956 | 0.85 | KCNH2 (0.53) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL5083807 | 0.83 | KDM4E (0.60) | ALDH1A1CHRM2KDM4EHPGDHSD17B10 | |
| SCHEMBL7164343 | 0.83 | KDM4E (0.60) | ALDH1A1CHRM2KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080044390-A1 | Methods and compositions for the treatment of neurodegenerative disorders | CHDI, INCORPORATED | 2008-02-21 | — | — | US | disclosed |
| US-6552196-B2 | Quinolone carboxylic acid derivatives | DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) | 2003-04-22 | — | — | US | disclosed |
| US-20020035258-A1 | Quinolone carboxylic acid derivatives | DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. | 2002-03-21 | — | — | US | disclosed |
| EP-0994878-B1 | QUINOLONE CARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM IND CO LTD (KR) | 2001-11-28 | — | — | EP | disclosed |
| US-6313299-B1 | ANTIBACTERIAL AGENTS EFFECTIVE AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AND STREPTOCOCCUS; 1,8-NAPHTHRYDINE DERIVATIVES | DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) | 2001-11-06 | — | — | US | disclosed |
| EP-0994878-A1 | QUINOLONE CARBOXYLIC ACID DERIVATIVES | DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999000393-A1 | QUINOLONE CARBOXYLIC ACID DERIVATIVES | DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) | 1999-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035258-A1 | Quinolone carboxylic acid derivatives | QARS1, QPCT, CNOT1 | ALDH1A1 985/4885POLB 3021/4885OPRM1 3204/4885 |
| US-20080044390-A1 | Methods and compositions for the treatment of neurodegenerative disorders | HTT, SNCA, NLN | ALDH1A1 2348/4885POLB 781/4885OPRM1 3844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.