SCHEMBL508633

SCHEMBL508633

CC(SSc1ccccn1)C(C(=O)O)N1C(=O)CCC1=O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 1/20 0.39
EHMT2 Q96KQ7 1/20 0.38
EHMT1 Q9H9B1 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
ALDH1A1 P00352 5/20 0.37
PKM P14618 1/20 0.37
SLC1A2 P43004 1/20 0.36
MAPT P10636 3/20 0.33
KMT2A Q03164 3/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
TSHR P16473 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 1/20 0.33
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29139343 0.81 ALDH1A1 (0.37) SMN1; SMN2HSD17B10HPGDEHMT2EHMT1
SCHEMBL745826 0.80 ALDH1A1 (0.46) SMN1; SMN2HSD17B10HPGDEHMT2EHMT1
Hydrogen Sulfide SCHEMBL17534845 0.79 ALDH1A1 (0.45) SMN1; SMN2HSD17B10HPGDEHMT2EHMT1
SCHEMBL10340551 0.78 ALDH1A1 (0.43) SMN1; SMN2HSD17B10HPGDEHMT2EHMT1
SCHEMBL6687766 0.77 ALDH1A1 (0.42) SMN1; SMN2HSD17B10HPGDEHMT2EHMT1
SCHEMBL1268139 0.74 SMN1; SMN2 (0.52) SMN1; SMN2HSD17B10HPGDEHMT2EHMT1
SCHEMBL44725 0.74 ALDH1A1 (0.50) SMN1; SMN2HSD17B10HPGDEHMT2EHMT1
SCHEMBL24599713 0.73 EHMT2 (0.59) SMN1; SMN2HSD17B10HPGDEHMT2EHMT1
SCHEMBL16132722 0.73 EHMT2 (0.59) SMN1; SMN2HSD17B10HPGDEHMT2EHMT1
SCHEMBL5153054 0.73 SMN1; SMN2 (0.39) SMN1; SMN2HSD17B10HPGDEHMT2EHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2804631-B1 SURROBODY CONJUGATES I2 PHARMACEUTICALS INC (US) 2021-03-17 EP claimed
EP-2914630-B1 NOVEL ANTIGEN BINDING PROTEINS AND THEIR USE AS ADDRESSING PRODUCT FOR THE TREATMENT OF CANCER PF MEDICAMENT (FR) 2021-03-03 EP claimed
EP-2804631-A1 SURROBODY COJUGATES Sea Lane Biotechnologies,llc. (US) 2014-11-26 EP claimed
WO-2013109994-A1 SURROBODY COJUGATES SEA LANE BIOTECHNOLOGIES, LLC (US) 2013-07-25 WO claimed
EP-2032172-B1 LEPTOMYCIN DERIVATIVES SANOFI SA (FR) 2012-06-06 EP claimed
EP-1813614-B1 Cytotoxic agents comprising new tomaymycin derivatives SANOFI SA (FR) 2011-10-05 EP claimed
US-7514078-B2 Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies CORNELL RESEARCH FOUNDATION, INC. (US) 2009-04-07 US claimed
US-20260144888-A1 USE OF A LIQUID AQUEOUS COMPOSITION FOR SOLUBILIZATION AND STABILIZATION OF AN ANTIBODY-DRUG CONJUGATE PIERRE FABRE MEDICAMENT (FR) 2026-05-28 US disclosed
EP-3620473-B1 NOVEL HETERODIMERIC PROTEINS XENCOR INC (US) 2026-05-27 EP disclosed
EP-4748862-A2 HETERODIMERIC PROTEINS Xencor, Inc. (US) 2026-05-27 EP disclosed
EP-4748856-A2 COMPOSITIONS AND METHODS FOR TREATING CANCER WITH SELF-DRIVING CHIMERIC ANTIGEN RECEPTORS Lentigen Technology, Inc. (US) 2026-05-27 EP disclosed
WO-2026100671-A1 ANTI-GPRC5A ANTIBODY AND USES THEREOF リベロセラ株式会社 2026-05-15 WO disclosed
EP-4739396-A1 HUMANIZED 40H3 ANTIBODY The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2026-05-13 EP disclosed
EP-0428534-B1 COUPLING AGENTS AND STERICALLY HINDERED DISULFIDE LINKED CONJUGATES PREPARED THEREFROM CETUS ONCOLOGY CORP (US) 1995-03-29 EP disclosed
US-5208020-A Cytotoxic agents comprising maytansinoids and their therapeutic use IMMUNOGEN INC. (US) 1993-05-04 US disclosed
EP-0528527-A2 Conjugates ZENECA LIMITED (GB) 1993-02-24 EP disclosed
US-5165923-A Anticarcinogenic agents by elimination of cells using a toxin conjugate IMPERIAL CANCER RESEARCH TECHNOLOGY (GB) 1992-11-24 US disclosed
EP-0502101-A1 COMPOSITIONS FOR THE TREATMENT OF HODGKIN'S DISEASE IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 1992-09-09 EP disclosed
WO-1991007941-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF HODGKIN'S DISEASE IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 1991-06-13 WO disclosed
WO-1991007437-A2 IMPROVED CD-30 ANTIBODIES AND FRAGMENTS THEREOF PARKER, DAVID, L. (US) 1991-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144888-A1 USE OF A LIQUID AQUEOUS COMPOSITION FOR SOLUBILIZATION AND STABILIZATION OF AN ANTIBODY-DRUG CONJUGATE IGF1R, CD44, MUC1 SMN1; SMN2 120/4885HSD17B10 3539/4885HPGD 4654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.