SCHEMBL5086384

SCHEMBL5086384

CCc1ccc(Cl)c(-c2cc(C)[c]cc2Br)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HTR1A P08908 9/20 0.32
HTR2B P41595 9/20 0.32
HTR7 P34969 8/20 0.32
HTR5A P47898 8/20 0.32
HTR1D P28221 7/20 0.32
HTR1B P28222 7/20 0.32
HTR2A P28223 7/20 0.32
HTR2C P28335 6/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4439963 0.79 IDO1 (0.38) ALDH1A1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL5086382 0.77 ALDH1A1 (0.33) ALDH1A1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL3664038 0.73 HTR2A (0.35) ALDH1A1MAPTSMN1; SMN2HPGDHTR2A
SCHEMBL3664036 0.71 CYP1A2 (0.35) ALDH1A1SMN1; SMN2KDM4E
SCHEMBL12188730 0.69 ABL1 (0.43) ALDH1A1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL11775112 0.69 CSNK2A2 (0.34) ALDH1A1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL13729360 0.68 NPC1 (0.41) ALDH1A1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL4439962 0.68 MEN1 (0.34) ALDH1A1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL5086321 0.67 ALKBH3 (0.36) ALDH1A1MAPTHPGDMEN1KMT2A
SCHEMBL257061 0.66 ALDH1A1 (0.42) ALDH1A1NPC1MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008091594-A2 FUNGICIDAL MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed