SCHEMBL5086453

SCHEMBL5086453

CCCCCc1cccc2c1[C]c1ccccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.44
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
ALOX5 P09917 1/20 0.40
PTGS2 P35354 1/20 0.40
BID P55957 3/20 0.38
MCL1 Q07820 3/20 0.38
BCL2L1 Q07817 2/20 0.38
BAK1 Q16611 2/20 0.38
KAT8 Q9H7Z6 2/20 0.38
PPARA Q07869 2/20 0.38
PPARG P37231 1/20 0.38
EP300 Q09472 1/20 0.38
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
KAT5 Q92993 1/20 0.38
SAE1 Q9UBE0 1/20 0.38
GPR3 P46089 1/20 0.37
ELANE P08246 2/20 0.36
CTSG P08311 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5090595 0.98 LIPG (0.46) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL5086715 0.98 LIPG (0.46) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL5083841 0.98 LIPG (0.46) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL5086305 0.98 LIPG (0.46) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL5087392 0.95 NR1H2 (0.38) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL5090001 0.88 ELANE (0.32) NR1H2NR1H3PPARAELANECTSG
SCHEMBL5090542 0.81 GABRA1 (0.39)
SCHEMBL8067200 0.78 CNR2 (0.41) LIPGNR1H2NR1H3BIDMCL1
SCHEMBL1024526 0.74 LIPG (0.59) LIPGNR1H2NR1H3ALOX5PTGS2
SCHEMBL9619382 0.73 LIPG (0.62) LIPGNR1H2NR1H3ALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1498178-B1 Transition metal complex and process for producing the same SUMITOMO CHEMICAL CO (JP) 2008-06-11 EP disclosed
EP-1498178-A2 Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex and process for producing olefin polymers Sumitomo Chemical Company, Limited (JP) 2005-01-19 EP disclosed
EP-0842939-B1 OLEFIN POLYMERIZATION CATALYST CONTAINING A TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6329478-B1 SOLUBILITY IN SATURATED HYDROCARBON SOLVENTS SUMITMO CHEMICAL COMPANY, LIMITED 2001-12-11 US disclosed
EP-0842939-A1 TRANSITION METAL COMPLEX, PROCESS FOR THE PREPARATION THEREOF, POLYMERIZATION CATALYST FOR OLEFINS CONTAINING THE COMPLEX, AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-05-20 EP disclosed