SCHEMBL5086524

SCHEMBL5086524

C=C(C)C(=O)OC(F)(C(F)(F)F)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2400720 0.94 ALDH1A1 (0.38) ALDH1A1TSHRTHRB
SCHEMBL28378224 0.92 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL7532269 0.92 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL55495 0.92 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL676250 0.92 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL2396171 0.92 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL28207691 0.92 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL5086534 0.92 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
SCHEMBL896745 0.92 ALDH1A1 (0.37) ALDH1A1TSHRTHRB
Fluoride SCHEMBL28924098 0.90 ALDH1A1 (0.35) ALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112662303-A Highly water-resistant resin composition for optical fiber coating 露温迪克埃蒂姆有限公司 2021-04-16 CN disclosed
US-9879153-B2 Anti-icing composite WANG LIANG (US) 2018-01-30 US disclosed
US-20160009971-A1 Anti-Icing Composite WANG LIANG (US) 2016-01-14 US disclosed
EP-1831305-B1 GRAFT COPOLYMERS WITH SEGMENTED ARMS COATINGS FOREIGN IP CO LLC (US) 2015-08-12 EP disclosed
US-7402624-B2 Graft copolymers with segmented arms and their preparation and use E.I. DU PONT DE NEMOURS & COMPANY (US) 2008-07-22 US disclosed
EP-1831305-A2 GRAFT COPOLYMERS WITH SEGMENTED ARMS AND THEIR PREPARATION AND USE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-09-12 EP disclosed
WO-2006052981-A2 GRAFT COPOLYMERS WITH SEGMENTED ARMS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-05-18 WO disclosed
US-20060100305-A1 Graft copolymers with segmented arms and their preparation and use AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2006-05-11 US disclosed
US-5855960-A POLYSILICATES; WEATHERPROOFING, ANTISOILANT PROTECTIVECOATING KANSAI PAINT CO., LTD. (JP) 1999-01-05 US disclosed
US-5635572-A ACID-TREATED FILM COMPRISING CURED PRODUCT OF HYDROXYL GROUP-CONTAINING RESIN, POLYISOCYANATE CURING AGENT, ORGANOSILICATE CONDENSATE; STAIN RESISTANCE, WEATHERPROOFING KANSAI PAINT CO., LTD. (JP) 1997-06-03 US disclosed