Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812566 | 1.00 | LMNA (0.31) | LMNA | |
| SCHEMBL8071570 | 0.80 | LMNA (0.33) | LMNA | |
| SCHEMBL8854144 | 0.80 | LMNA (0.33) | LMNA | |
| SCHEMBL2239686 | 0.77 | — | — | |
| SCHEMBL8902834 | 0.77 | — | — | |
| SCHEMBL4391933 | 0.77 | — | — | |
| SCHEMBL26626961 | 0.76 | LMNA (0.31) | LMNA | |
| SCHEMBL9727393 | 0.76 | THRB (0.31) | LMNA | |
| SCHEMBL5788572 | 0.76 | LMNA (0.31) | LMNA | |
| SCHEMBL25980493 | 0.76 | LMNA (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10000703-A | — | — | None | — | — | JP | disclosed |
| US-7354985-B2 | Fluorinated thermoset polyurethane elastomers prepared from polyether prepolymers formed from mono-substituted fluorinated oxetane monomers | AEROJET ROCKETDYNE, INC. (F/K/A AEROJET-GENERAL CORPORATION) | 2008-04-08 | — | — | US | disclosed |
| EP-0811004-B1 | MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS | AEROJET GENERAL CO (US) | 2006-12-06 | — | — | EP | disclosed |
| US-6891013-B1 | Fluorinated polyurethane elastomers prepared from polyether prepolymers formed from mono-substituted fluorinated oxetane monomers and tetrahydrofuran | AEROJET-GENERAL CORPORATION (US) | 2005-05-10 | — | — | US | disclosed |
| US-20040087759-A1 | Fluorinated thermoset polyurethane elastomers prepared from polyether prepolymers formed mono-substituted fluorinated oxetane monomers | AEROJET ROCKETDYNE, INC. (F/K/A AEROJET-GENERAL CORPORATION) | 2004-05-06 | — | — | US | disclosed |
| US-6448368-B1 | HYDROXY TERMINATED POLYETHERS HAVING ASYMMETRIC PENDANT ALKOXYMETHYLENE GROUPS; HYDROPHOBIC; PREPARATION OF POLYURETHANE ELASTOMERS, THERMOSET PLASTICS AND COATINGS | AEROJET-GENERAL CORPORATION | 2002-09-10 | — | — | US | disclosed |
| US-6417314-B1 | WEAR RESISTANCE, TEAR AND BONDING STRENGTH; COATINGS, PLASTICS | AEROJET-GENERAL CORPORATION | 2002-07-09 | — | — | US | disclosed |
| US-6380351-B1 | FLUORINATED POLYETHERS | AEROJET-GENERAL CORPORATION | 2002-04-30 | — | — | US | disclosed |
| US-6037483-A | CHARGING REACTION VESSEL WITH AQUEOUS MIXTURE OF MONO-SUBSTITURED OXETANE, FLUOROALCOHOL, PHASE TRANSFER CATALYST AND STRONG BASE TO FORM REACTION MIXTURE; HEATING UNTIL REACTION IS COMPLETE | AEROJET-GENERAL CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |
| US-5807977-A | Polyoxetanes based on pendant perfluoroalkyl side chains such as 3-methyl-3-(2,2,2-trifluoroethoxymethyl)-oxetane to form polyethers; very low surface energy, high hydrophobicity, low glass transition temperature and low coefficient of friction | AEROJET GENERAL CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |
| JP-H10703-A | URETHANE RUBBER ROLL | MEIJI RUBBER & CHEM CO LTD | 1998-01-06 | — | — | JP | disclosed |
| US-5703194-A | WATERPROOFING; TEAR STRENGTH; BONDING STRENGTH | AEROJET-GENERAL CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |
| US-5668250-A | Polyether coprepolymers formed from mono-substituted fluorinated oxetane monomers and tetrahydrofuran | AEROJET-GENERAL CORPORATION (US) | 1997-09-16 | — | — | US | disclosed |
| US-5668251-A | Preparation of co-prepolymers from mono-substituted fluorinated monomers and tetrahydrofuran | AEROJET-GENERAL CORPORATION (US) | 1997-09-16 | — | — | US | disclosed |
| US-5654450-A | THERMOPLASTIC RESIN INTERMEDIATES; TEAR STRENGTH, ADHESION | AEROJET-GENERAL CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |
| US-5650483-A | PREPARING A SOLUTION OF A CATALYST, AN INITIATOR AND A SOLVENT, CONTACTING SOLUTION WITH A SECOND SOLUTION CONTAINING FLUORINATED OXETANE MONOMER(S) AND CONTROLLING THE TEMPERATURE OF THE MIXTURE | AEROJET-GENERAL CORPORATION (US) | 1997-07-22 | — | — | US | disclosed |
| US-5637772-A | OIL REPELLENT COATINGS; ANTIFOULING AGENTS; RELEASE AGENTS; ENCAPSULATION OF ELECTRICAL DEVICES; CURING AGENT FOR EPOXIDES | AEROJET GENERAL CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| WO-1996021657-A1 | MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS | AEROJET-GENERAL CORPORATION (US) | 1996-07-18 | — | — | WO | disclosed |